Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM053256-02
Application #
2192590
Study Section
Experimental Immunology Study Section (EI)
Project Start
1995-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Behrens, Edward M; Koretzky, Gary A (2017) Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era. Arthritis Rheumatol 69:1135-1143
Chang, John T; Ciocca, Maria L; Kinjyo, Ichiko et al. (2011) Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity 34:492-504
Juntilla, Marisa M; Koretzky, Gary A (2008) Critical roles of the PI3K/Akt signaling pathway in T cell development. Immunol Lett 116:104-10
Jordan, Martha S; Smith, Jennifer E; Burns, Jeremy C et al. (2008) Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. Immunity 28:359-69
Hunter, A J; Ottoson, N; Boerth, N et al. (2000) Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration. J Immunol 164:1143-7
Myung, P S; Clements, J L; White, D W et al. (2000) In vitro and in vivo macrophage function can occur independently of SLP-76. Int Immunol 12:887-97
Boerth, N J; Sadler, J J; Bauer, D E et al. (2000) Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling. J Exp Med 192:1047-58
Boerth, N J; Judd, B A; Koretzky, G A (2000) Functional association between SLAP-130 and SLP-76 in Jurkat T cells. J Biol Chem 275:5143-52
Fang, N; Koretzky, G A (1999) SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity. J Biol Chem 274:16206-12
Peterson, E J; Latinis, K M; Koretzky, G A (1998) Molecular characterization of a CD95 signaling mutant. Arthritis Rheum 41:1047-53

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