Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM062643-05
Application #
6387299
Study Section
Biochemistry Study Section (BIO)
Program Officer
Wolfe, Paul B
Project Start
1996-06-01
Project End
2004-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
5
Fiscal Year
2001
Total Cost
$237,192
Indirect Cost
Name
University of Miami School of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Rupesh, Kanchi Ravi; Smith, Aaron; Boehmer, Paul E (2014) Ligand induced stabilization of the melting temperature of the HSV-1 single-strand DNA binding protein using the thermal shift assay. Biochem Biophys Res Commun 454:604-8
Hsieh, Jui-Cheng; Kuta, Ryan; Armour, Courtney R et al. (2014) Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome. Virology 460-461:45-54
Bogani, Federica; Corredeira, Ilsa; Fernandez, Virneliz et al. (2010) Association between the herpes simplex virus-1 DNA polymerase and uracil DNA glycosylase. J Biol Chem 285:27664-72
Bogani, Federica; Chua, Chian New; Boehmer, Paul E (2009) Reconstitution of uracil DNA glycosylase-initiated base excision repair in herpes simplex virus-1. J Biol Chem 284:16784-90
Bogani, Federica; Boehmer, Paul E (2008) The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5'-deoxyribose phosphate lyase activities. Proc Natl Acad Sci U S A 105:11709-14
Nimonkar, A V; Le Gac, N Tanguy; Villani, G et al. (2006) Escherichia coli RecA promotes strand invasion with cisplatin-damaged DNA. Biochimie 88:535-42
Boehmer, Paul E (2004) RNA binding and R-loop formation by the herpes simplex virus type-1 single-stranded DNA-binding protein (ICP8). Nucleic Acids Res 32:4576-84
Nimonkar, Amitabh V; Boehmer, Paul E (2004) Role of protein-protein interactions during herpes simplex virus type 1 recombination-dependent replication. J Biol Chem 279:21957-65
Arana, Mercedes E; Song, Liping; Tanguy Le Gac, Nicolas et al. (2004) On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase. DNA Repair (Amst) 3:659-69
Nimonkar, Amitabh V; Boehmer, Paul E (2003) Reconstitution of recombination-dependent DNA synthesis in herpes simplex virus 1. Proc Natl Acad Sci U S A 100:10201-6

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