Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM081607-03
Application #
7770861
Study Section
Cancer Molecular Pathobiology Study Section (CAMP)
Program Officer
Zatz, Marion M
Project Start
2008-05-01
Project End
2012-02-29
Budget Start
2010-03-01
Budget End
2011-02-28
Support Year
3
Fiscal Year
2010
Total Cost
$317,824
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Herr, Anabel; Longworth, Michelle; Ji, Jun-Yuan et al. (2012) Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation. Dev Dyn 241:1695-707
Zhang, Jinghui; Benavente, Claudia A; McEvoy, Justina et al. (2012) A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature 481:329-34
Manning, Amity L; Dyson, Nicholas J (2012) RB: mitotic implications of a tumour suppressor. Nat Rev Cancer 12:220-6
Tschöp, Katrin; Conery, Andrew R; Litovchick, Larisa et al. (2011) A kinase shRNA screen links LATS2 and the pRB tumor suppressor. Genes Dev 25:814-30
Di Stefano, Luisa; Walker, James A; Burgio, Giosalba et al. (2011) Functional antagonism between histone H3K4 demethylases in vivo. Genes Dev 25:17-28
Popova, Milena K; He, Wei; Korenjak, Michael et al. (2011) Rb deficiency during Drosophila eye development deregulates EMC, causing defects in the development of photoreceptors and cone cells. J Cell Sci 124:4203-12
Manning, Amity L; Dyson, Nicholas J (2011) pRB, a tumor suppressor with a stabilizing presence. Trends Cell Biol 21:433-41
Centore, Richard C; Havens, Courtney G; Manning, Amity L et al. (2010) CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase. Mol Cell 40:22-33
Manning, Amity L; Longworth, Michelle S; Dyson, Nicholas J (2010) Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev 24:1364-76
Zhang, Jianmin; Ji, Jun-Yuan; Yu, Min et al. (2009) YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol 11:1444-50

Showing the most recent 10 out of 12 publications