In sum, overall the project suffered an estimated 3-4 month set-back. We have requested supplementary funding for 3 months (one quarter of the total direct award or $47,500) to cover this setback by recouping lost time (postdoc and PI salary) and reagents and lab supplies required to recover experiments that were on-going at the time of the storm and to test (and remake, if necessary) reagents for future use.

Public Health Relevance

Environmental factors impact reproduction. This application follows from our surprising discovery that the environment can influence fertility by way of chemosensory neurons and a conserved TGF? signaling pathway in C. elegans. Our studies will likely benefit human health since the cellular and molecular mechanisms underlying these controls are evolutionarily conserved.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM102254-02S1
Application #
8666481
Study Section
Cellular, Molecular and Integrative Reproduction Study Section (CMIR)
Program Officer
Haynes, Susan R
Project Start
2014-01-01
Project End
2015-12-31
Budget Start
2014-01-01
Budget End
2015-12-31
Support Year
2
Fiscal Year
2014
Total Cost
$26,837
Indirect Cost
$11,004
Name
New York University
Department
Pathology
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Hubbard, E Jane Albert (2014) FLP/FRT and Cre/lox recombination technology in C. elegans. Methods 68:417-24