Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD015842-13
Application #
2197254
Study Section
Reproductive Biology Study Section (REB)
Project Start
1983-01-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
13
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Storey, B T; Alvarez, J G; Thompson, K A (1998) Human sperm glutathione reductase activity in situ reveals limitation in the glutathione antioxidant defense system due to supply of NADPH. Mol Reprod Dev 49:400-7
Storey, B T (1997) Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa. Mol Hum Reprod 3:203-13
Alvarez, J G; Storey, B T (1995) Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa. Mol Reprod Dev 42:334-46
Lasso, J L; Noiles, E E; Alvarez, J G et al. (1994) Mechanism of superoxide dismutase loss from human sperm cells during cryopreservation. J Androl 15:255-65
Alvarez, J G; Ludmir, J (1993) Semiautomated multisample analysis of amniotic fluid lipids by high-performance thin-layer chromatography-reflectance spectrodensitometry. J Chromatogr 615:142-7
Alvarez, J G; Touchstone, J C (1992) Separation of acidic and neutral lipids by aminopropyl-bonded silica gel column chromatography. J Chromatogr 577:142-5
Alvarez, J G; Storey, B T; Hemling, M L et al. (1990) High-resolution proton nuclear magnetic resonance characterization of seminolipid from bovine spermatozoa. J Lipid Res 31:1073-81
Alvarez, J G; Storey, B T (1989) Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation. Gamete Res 23:77-90
Alvarez, J G; Lee, M A; Iozzo, R V et al. (1988) Ethanol accelerates acrosomal loss in human spermatozoa. J Androl 9:357-66
Alvarez, J G; Touchstone, J C (1988) Separation of acidic and neutral glycolipids by diphasic thin-layer chromatography. J Chromatogr 436:515-6

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