Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD026871-05
Application #
2200125
Study Section
Nutrition Study Section (NTN)
Project Start
1991-03-05
Project End
1997-02-28
Budget Start
1995-03-01
Budget End
1997-02-28
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Pediatrics
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Savendahl, L; Underwood, L E (1999) Fasting increases serum total cholesterol, LDL cholesterol and apolipoprotein B in healthy, nonobese humans. J Nutr 129:2005-8
Chrysis, D; Moats-Staats, B M; Underwood, L E (1998) Effect of fasting on insulin receptor-related receptor messenger ribonucleic acid in rat kidney. J Endocrinol 159:R9-R12
Ninh, N X; Maiter, D; Lause, P et al. (1998) Continuous administration of growth hormone does not prevent the decrease of IGF-I gene expression in zinc-deprived rats despite normalization of liver GH binding. Growth Horm IGF Res 8:465-72
Zhang, J; Chrysis, D; Underwood, L E (1998) Reduction of hepatic insulin-like growth factor I (IGF-I) messenger ribonucleic acid (mRNA) during fasting is associated with diminished splicing of IGF-I pre-mRNA and decreased stability of cytoplasmic IGF-I mRNA. Endocrinology 139:4523-30
Smith, W J; Underwood, L E; Keyes, L et al. (1997) Use of insulin-like growth factor I (IGF-I) and IGF-binding protein measurements to monitor feeding of premature infants. J Clin Endocrinol Metab 82:3982-8
Savendahl, L; Underwood, L E (1997) Decreased interleukin-2 production from cultured peripheral blood mononuclear cells in human acute starvation. J Clin Endocrinol Metab 82:1177-80
Savendahl, L; Mar, M H; Underwood, L E et al. (1997) Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction. Am J Clin Nutr 66:622-5
Savendahl, L; Underwood, L E; Haldeman, K M et al. (1997) Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid. Endocrinology 138:734-40
Muaku, S M; Beauloye, V; Thissen, J P et al. (1996) Long-term effects of gestational protein malnutrition on postnatal growth, insulin-like growth factor (IGF)-I, and IGF-binding proteins in rat progeny. Pediatr Res 39:649-55
Underwood, L E (1996) Nutritional regulation of IGF-I and IGFBPs. J Pediatr Endocrinol Metab 9 Suppl 3:303-12

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