Fecal incontinence is thought to be a common condition with profound social impact. Obstetric delivery is thought to be the leading contributor to development of fecal incontinence in women. There are no population-based studies of fecal incontinence following childbirth; the highest-risk period. Previous studies examining postpartum fecal incontinence are from single institutions, populations that are subject to referral bias, and small numbers; making generalizability of the results impossible. The primary goal of this proposal is to provide population-based information on incidence, and risk factors with essential correlation with anatomic/physiologic findings and longitudinal follow-up.
The specific aims of this proposal are to: - Provide population-based estimates of incidence of fecal incontinence in all postpartum women delivering in Oregon state. - Identify contributing modifiable and non-modifiable risk factors for the development of postpartum fecal incontinence. - Explore in depth a possible causal relationship between obstetric delivery methods and postpartum fecal incontinence. - Develop a cohort of women with postpartum fecal incontinence to follow longitudinally to identify factors that predict the likelihood of resolution, recurrence or worsening of symptoms. - Correlate anatomic and physiologic findings to symptoms of fecal incontinence. - Understand the physical, psychological, social ramifications of fecal incontinence. These data will provide a better understanding of the extent of the problem and will provide data essential for future trials of prevention and treatment of fecal incontinence.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD041139-03
Application #
6655719
Study Section
Special Emphasis Panel (ZHD1-DRG-D (12))
Program Officer
Weber, Anne M
Project Start
2001-08-07
Project End
2005-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
3
Fiscal Year
2003
Total Cost
$351,075
Indirect Cost
Name
Oregon Health and Science University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Lo, Jamie; Osterweil, Patty; Li, Hong et al. (2010) Quality of life in women with postpartum anal incontinence. Obstet Gynecol 115:809-14
Boyles, Sarah Hamilton; Li, Hong; Mori, Tomi et al. (2009) Effect of mode of delivery on the incidence of urinary incontinence in primiparous women. Obstet Gynecol 113:134-41
Guise, Jeanne-Marie; Boyles, Sarah Hamilton; Osterweil, Patricia et al. (2009) Does cesarean protect against fecal incontinence in primiparous women? Int Urogynecol J Pelvic Floor Dysfunct 20:61-7
Guise, Jeanne-Marie; Morris, Cynthia; Osterweil, Patricia et al. (2007) Incidence of fecal incontinence after childbirth. Obstet Gynecol 109:281-8
Hall, Wendy; McCracken, Karen; Osterweil, Patricia et al. (2003) Frequency and predictors for postpartum fecal incontinence. Am J Obstet Gynecol 188:1205-7