The purpose of this longitudinal study is to evaluate a developmentally-oriented bio-neuropsychosocial model of psychological adjustment in young adolescents with spina bifida (10-13 years old at Time 1 and 12-15 years old at Time 2). Extensive multi-source and multi-method data will be collected across several predictor variable domains: (1) biological, (2) neuropsychological, and (3) social. A multidimensional perspective on adolescent adjustment will also be adopted, with a rigorous focus on the adolescents' social adjustment. The proposed study will be the first to collect observed peer, interaction data (target child with close friend) in adolescents with spina bifida. The degree to which neuropsychological limitations experienced by children with spina bifida contribute to their social difficulties and other psychological problems will also be examined. Participants will include a sample of 140 children and young adolescents with spina bifida (with meningomyelocele and shunted hydrocephalus) along with their parents, a close friend, teachers, and health professionals. Spanish-speaking Hispanic/Latino families will also be recruited. Questionnaire, interview, neuropsychological testing, and observational methods will be employed during two home visits at Time 1 and two home visits at Time 2. In addition to evaluating the utility of the bioneuropsychosocial model, several mediational and moderational models will also be tested within the context of the more general model. Such models will facilitate identification of underlying mechanisms for associations between variables (i.e., mediational models) and will attempt to isolate variables within one domain that compensate for deficits in another domain (i.e., moderational models). Findings of this study will provide information on the differential relevance of family relationships, peer relationships, neuropsychological factors, and biological factors for adjustment in adolescents with spina bifida. Moreover, the results will have implications for prevention and intervention efforts with families who have offspring with disabling birth defects. ? ?

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
1R01HD048629-01A1
Application #
6984277
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Oster-Granite, Mary Lou
Project Start
2005-09-15
Project End
2010-07-31
Budget Start
2005-09-15
Budget End
2006-07-31
Support Year
1
Fiscal Year
2005
Total Cost
$337,200
Indirect Cost
Name
Loyola University Chicago
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
074368911
City
Chicago
State
IL
Country
United States
Zip Code
60660
Holbein, Christina E; Peugh, James L; Holmbeck, Grayson N (2017) Social Skills in Youth With Spina Bifida: A Longitudinal Multimethod Investigation Comparing Biopsychosocial Predictors. J Pediatr Psychol 42:1133-1143
Wasserman, Rachel M; Stoner, Alison M; Stern, Alexa et al. (2016) ADHD and Attention Problems in Children With and Without Spina Bifida. Top Spinal Cord Inj Rehabil 22:253-259
Lennon, Jaclyn M; Klages, Kimberly L; Amaro, Christina M et al. (2015) Longitudinal study of neuropsychological functioning and internalizing symptoms in youth with spina bifida: social competence as a mediator. J Pediatr Psychol 40:336-48
Lennon, Jaclyn M; Murray, Caitlin B; Bechtel, Colleen F et al. (2015) Resilience and Disruption in Observed Family Interactions in Youth With and Without Spina Bifida: An Eight-Year, Five-Wave Longitudinal Study. J Pediatr Psychol 40:943-55
Holbein, Christina E; Lennon, Jaclyn M; Kolbuck, Victoria D et al. (2015) Observed differences in social behaviors exhibited in peer interactions between youth with spina bifida and their peers: neuropsychological correlates. J Pediatr Psychol 40:320-35
Helgeson, Vicki S; Holmbeck, Grayson N (2015) An introduction to the special issue on peer relations in youth with chronic illness. J Pediatr Psychol 40:267-71
Psihogios, Alexandra M; Kolbuck, Victoria; Holmbeck, Grayson N (2015) Condition Self-Management in Pediatric Spina Bifida: A Longitudinal Investigation of Medical Adherence, Responsibility-Sharing, and Independence Skills. J Pediatr Psychol 40:790-803
Copp, Andrew J; Adzick, N Scott; Chitty, Lyn S et al. (2015) Spina bifida. Nat Rev Dis Primers 1:15007
Murray, Caitlin B; Amaro, Christina M; Devine, Katie A et al. (2015) Observed macro- and micro-level parenting behaviors during preadolescent family interactions as predictors of adjustment in emerging adults with and without spina bifida. J Pediatr Psychol 40:18-32
Murray, Caitlin B; Holmbeck, Grayson N; Ros, Anna M et al. (2015) A longitudinal examination of health-related quality of life in children and adolescents with spina bifida. J Pediatr Psychol 40:419-30

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