Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL016318-37
Application #
2214971
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1978-09-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
37
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Pharmacology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Dixon, J F; Hokin, L E (1998) Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex. Proc Natl Acad Sci U S A 95:8363-8
Dixon, J F; Hokin, L E (1997) The antibipolar drug valproate mimics lithium in stimulating glutamate release and inositol 1,4,5-trisphosphate accumulation in brain cortex slices but not accumulation of inositol monophosphates and bisphosphates. Proc Natl Acad Sci U S A 94:4757-60
Hokin, L E (1996) History of phosphoinositide research. Subcell Biochem 26:1-41
Los, G V; Artemenko, I P; Hokin, L E (1996) Phosphoinositide signalling in human neuroblastoma cells: biphasic effect of Li+ on the level of the inositolphosphate second messengers. Adv Enzyme Regul 36:245-64
Hokin, L E; Dixon, J F; Los, G V (1996) A novel action of lithium: stimulation of glutamate release and inositol 1,4,5 trisphosphate accumulation via activation of the N-methyl D-aspartate receptor in monkey and mouse cerebral cortex slices. Adv Enzyme Regul 36:229-44
Los, G V; Artemenko, I P; Hokin, L E (1995) Time-dependent effects of lithium on the agonist-stimulated accumulation of second messenger inositol 1,4,5-trisphosphate in SH-SY5Y human neuroblastoma cells. Biochem J 311 ( Pt 1):225-32
Dixon, J F; Los, G V; Hokin, L E (1994) Lithium stimulates glutamate ""release"" and inositol 1,4,5-trisphosphate accumulation via activation of the N-methyl-D-aspartate receptor in monkey and mouse cerebral cortex slices. Proc Natl Acad Sci U S A 91:8358-62
Su, X; Chen, F; Hokin, L E (1994) Cloning and expression of a novel, highly truncated phosphoinositide-specific phospholipase C cDNA from embryos of the brine shrimp, Artemia. J Biol Chem 269:12925-31
Dixon, J F; Hokin, L E (1994) Lithium stimulates accumulation of second-messenger inositol 1,4,5-trisphosphate and other inositol phosphates in mouse pancreatic minilobules without inositol supplementation. Biochem J 304 ( Pt 1):251-8
Hokin, L E (1993) Lithium increases accumulation of second messenger inositol 1,4,5-trisphosphate in brain cortex slices in species ranging from mouse to monkey. Adv Enzyme Regul 33:299-312

Showing the most recent 10 out of 32 publications