Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL016361-17
Application #
2214978
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1976-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
17
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195

  Publications

Shainoff, John R; Smejkal, Gary B; DiBello, Patricia M et al. (2002) Allosteric effects potentiating the release of the second fibrinopeptide A from fibrinogen by thrombin. J Biol Chem 277:19367-73
Mitkevich, O V; Shainoff, J R; DiBello, P M et al. (1998) Coagulation factor XIIIa undergoes a conformational change evoked by glutamine substrate. Studies on kinetics of inhibition and binding of XIIIA by a cross-reacting antifibrinogen antibody. J Biol Chem 273:14387-91
Smejkal, G B; Shainoff, J R (1997) Enhanced digital imaging of diaminobenzidene-stained immunoblots. Biotechniques 22:462
Odrljin, T M; Shainoff, J R; Lawrence, S O et al. (1996) Thrombin cleavage enhances exposure of a heparin binding domain in the N-terminus of the fibrin beta chain. Blood 88:2050-61
Mitkevich, O V; Sobel, J H; Shainoff, J R et al. (1996) Monoclonal antibody directed to a fibrinogen A alpha #529-539 epitope inhibits alpha-chain crosslinking by transglutaminases. Blood Coagul Fibrinolysis 7:85-92
Shainoff, J R; Smejkal, G B; Mitkevich, O et al. (1996) Preparative electrophoresis on linear polyacrylamide-agarose composite gels. Electrophoresis 17:179-84
Shainoff, J R; Smejkal, G B; DiBello, P M et al. (1996) Isolation and characterization of the fibrin intermediate arising from cleavage of one fibrinopeptide A from fibrinogen. J Biol Chem 271:24129-37
Shainoff, J R; Estafanous, F G; Yared, J P et al. (1994) Low factor XIIIA levels are associated with increased blood loss after coronary artery bypass grafting. J Thorac Cardiovasc Surg 108:437-45
Shainoff, J R; Urbanic, D A; DiBello, P M et al. (1993) GPR-phoresis, a novel approach to determining fibrin monomer and other macromolecular derivatives of fibrinogen and fibrin in blood. Blood Coagul Fibrinolysis 4:87-92
Valenzuela, R; Shainoff, J R; DiBello, P M et al. (1992) Immunoelectrophoretic and immunohistochemical characterizations of fibrinogen derivatives in atherosclerotic aortic intimas and vascular prosthesis pseudo-intimas. Am J Pathol 141:861-80

Showing the most recent 10 out of 17 publications