Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL031175-13
Application #
2216784
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1984-06-01
Project End
2000-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Feng, Nan-Hsiung; Lin, Hen-I; Wang, Jinn-Shyan et al. (2005) Differential expression of a V-type ATPase C subunit gene, Atp6v1c2, during culture of rat lung type II pneumocytes. J Biomed Sci 12:899-911
Homer, Robert J; Zheng, Tao; Chupp, Geoff et al. (2002) Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure. Am J Physiol Lung Cell Mol Physiol 283:L52-9
Gobran, L I; Rooney, S A (2001) Regulation of SP-B and SP-C secretion in rat type II cells in primary culture. Am J Physiol Lung Cell Mol Physiol 281:L1413-9
Rooney, S A (2001) Regulation of surfactant secretion. Comp Biochem Physiol A Mol Integr Physiol 129:233-43
Isohama, Y; Rooney, S A (2001) Glucocorticoid enhances the response of type II cells from newborn rats to surfactant secretagogues. Biochim Biophys Acta 1531:241-50
Gobran, L I; Rooney, S A (1999) Surfactant secretagogue activation of protein kinase C isoforms in cultured rat type II cells. Am J Physiol 277:L251-6
Gobran, L I; Xu, Z X; Rooney, S A (1998) PKC isoforms and other signaling proteins involved in surfactant secretion in developing rat type II cells. Am J Physiol 274:L901-7
Gobran, L I; Rooney, S A (1997) Adenylate cyclase-coupled ATP receptor and surfactant secretion in type II pneumocytes from newborn rats. Am J Physiol 272:L187-96
Rooney, S A; Gobran, L I (1997) Influence of the protein kinase C inhibitor 3-[1-[3-(amidinothio) propyl]-1H-indoyl-3-yl]-3-(1-methyl-1H-indoyl-3-yl) maleimide methane sulfonate (Ro-318220) on surfactant secretion in type II pneumocytes. Biochem Pharmacol 53:597-601
Gobran, L I; Xu, Z X; Lu, Z et al. (1994) P2u purinoceptor stimulation of surfactant secretion coupled to phosphatidylcholine hydrolysis in type II cells. Am J Physiol 267:L625-33

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