Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL035034-14
Application #
2217724
Study Section
Physiology Study Section (PHY)
Project Start
1985-04-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Biology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
McDonough, Stefan I; Mori, Yasuo; Bean, Bruce P (2005) FPL 64176 modification of Ca(V)1.2 L-type calcium channels: dissociation of effects on ionic current and gating current. Biophys J 88:211-23
Blair, Nathaniel T; Bean, Bruce P (2003) Role of tetrodotoxin-resistant Na+ current slow inactivation in adaptation of action potential firing in small-diameter dorsal root ganglion neurons. J Neurosci 23:10338-50
Mitterdorfer, Jorg; Bean, Bruce P (2002) Potassium currents during the action potential of hippocampal CA3 neurons. J Neurosci 22:10106-15
Blair, Nathaniel T; Bean, Bruce P (2002) Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons. J Neurosci 22:10277-90
McDonough, Stefan I; Boland, Linda M; Mintz, Isabelle M et al. (2002) Interactions among toxins that inhibit N-type and P-type calcium channels. J Gen Physiol 119:313-28
Greif, G J; Sodickson, D L; Bean, B P et al. (2000) Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o). J Neurophysiol 83:1010-8
Sodickson, D L; Bean, B P (1998) Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors. J Neurosci 18:8153-62
Raman, I M; Bean, B P (1997) Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J Neurosci 17:4517-26
McDonough, S I; Mintz, I M; Bean, B P (1997) Alteration of P-type calcium channel gating by the spider toxin omega-Aga-IVA. Biophys J 72:2117-28
McDonough, S I; Lampe, R A; Keith, R A et al. (1997) Voltage-dependent inhibition of N- and P-type calcium channels by the peptide toxin omega-grammotoxin-SIA. Mol Pharmacol 52:1095-104

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