Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL035561-11
Application #
2217856
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1985-09-30
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Kun, Ernest; Kirsten, Eva; Bauer, Pal I et al. (2006) Quantitative correlation between cellular proliferation and nuclear poly (ADP-ribose) polymerase (PARP-1). Int J Mol Med 17:293-300
Bauer, Pal I; Kenesi, Erzsebet; Mendeleyev, Jerome et al. (2005) The influence of ATP on poly(ADP-ribose) metabolism. Int J Mol Med 16:321-4
Bauer, Pal I; Kirsten, Eva; Kun, Ernest (2005) Mechanisms of antitumor action of methyl-3,5-diiodo-4-(4'-methoxyphenoxy)benzoate: drug-induced protein dephosphorylations and inhibition of the permissive action of ceramide on growth factor induced cell proliferation. Oncol Rep 13:465-8
Huang, Kai; Tidyman, William E; Le, Kim-Uyen T et al. (2004) Analysis of nucleotide sequence-dependent DNA binding of poly(ADP-ribose) polymerase in a purified system. Biochemistry 43:217-23
Kun, Ernest; Kirsten, Eva; Mendeleyev, Jerome et al. (2004) Regulation of the enzymatic catalysis of poly(ADP-ribose) polymerase by dsDNA, polyamines, Mg2+, Ca2+, histones H1 and H3, and ATP. Biochemistry 43:210-6
Kirsten, Eva; Kun, Ernest; Mendeleyev, Jerome et al. (2004) Activity assays for poly-ADP ribose polymerase. Methods Mol Biol 287:137-49
Tidyman, William E; Sehnert, Amy J; Huq, Anja et al. (2003) In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos. Dev Dyn 227:484-96
Kun, Ernest; Kirsten, Eva; Ordahl, Charles P (2002) Coenzymatic activity of randomly broken or intact double-stranded DNAs in auto and histone H1 trans-poly(ADP-ribosylation), catalyzed by poly(ADP-ribose) polymerase (PARP I). J Biol Chem 277:39066-9
Butler, A J; Ordahl, C P (1999) Poly(ADP-ribose) polymerase binds with transcription enhancer factor 1 to MCAT1 elements to regulate muscle-specific transcription. Mol Cell Biol 19:296-306
Dockter, J L; Ordahl, C P (1998) Determination of sclerotome to the cartilage fate. Development 125:2113-24

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