Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL038291-10
Application #
2218778
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1988-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Wickley, Peter J; Shiga, Toshiya; Murray, Paul A et al. (2007) Propofol modulates Na+-Ca2+ exchange activity via activation of protein kinase C in diabetic cardiomyocytes. Anesthesiology 106:302-11
Ding, Xueqin; Murray, Paul A (2007) Acetylcholine activates protein kinase C-alpha in pulmonary venous smooth muscle. Anesthesiology 106:507-14
Ding, Xueqin; Murray, Paul A (2007) The differential effects of intravenous anesthetics on myofilament Ca2+ sensitivity in pulmonary venous smooth muscle. Anesth Analg 105:1278-86, table of contents
Shimizu, Sachiko; Ding, Xueqin; Murray, Paul A (2006) Intravenous anesthetics inhibit capacitative calcium entry in pulmonary venous smooth muscle cells. Anesthesiology 104:791-7
Kanaya, Noriaki; Murray, Paul A; Damron, Derek S (2006) Effects of L-type Ca2+ channel modulation on direct myocardial effects of diazepam and midazolam in adult rat ventricular myocytes. J Anesth 20:17-25
Roh, Woon-Seok; Ding, Xueqin; Murray, Paul A (2006) Propofol and thiopental attenuate adenosine triphosphate-sensitive potassium channel relaxation in pulmonary veins. Am J Physiol Lung Cell Mol Physiol 291:L636-43
Wickley, Peter J; Ding, Xueqin; Murray, Paul A et al. (2006) Propofol-induced activation of protein kinase C isoforms in adult rat ventricular myocytes. Anesthesiology 104:970-7
Wickley, Peter J; Shiga, Toshiya; Murray, Paul A et al. (2006) Propofol decreases myofilament Ca2+ sensitivity via a protein kinase C-, nitric oxide synthase-dependent pathway in diabetic cardiomyocytes. Anesthesiology 104:978-87
Ding, Xueqin; Murray, Paul A (2005) Cellular mechanisms of thromboxane A2-mediated contraction in pulmonary veins. Am J Physiol Lung Cell Mol Physiol 289:L825-33
Gable, Brad D; Shiga, Toshiya; Murray, Paul A et al. (2005) Propofol increases contractility during alpha1a-adrenoreceptor activation in adult rat cardiomyocytes. Anesthesiology 103:335-43

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