Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050180-03
Application #
2226293
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1993-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Physiology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Lahiri, S; Mitchell, C H; Reigada, D et al. (2007) Purines, the carotid body and respiration. Respir Physiol Neurobiol 157:123-9
Lahiri, S; Roy, A; Baby, S M et al. (2006) Oxygen sensing in the body. Prog Biophys Mol Biol 91:249-86
Lahiri, S; Roy, A; Li, J et al. (2004) Role of Fe2+ in oxygen sensing in the carotid body. Adv Exp Med Biol 551:59-64
Roy, Arijit; Li, Jingqing; Baby, Santhosh M et al. (2004) Effects of iron-chelators on ion-channels and HIF-1alpha in the carotid body. Respir Physiol Neurobiol 141:115-23
Lahiri, Sukhamay; Roy, Arijit; Li, Jinquing et al. (2003) Ca2+ responses to hypoxia are mediated by IP3-R on Ca2+ store depletion. Adv Exp Med Biol 536:25-32
Di Giulio, C; Huang, W X; Mokashi, A et al. (2003) Sustained hypoxia promotes hyperactive response of carotid body in the cat. Respir Physiol Neurobiol 134:69-74
Mokashi, A; Li, J; Roy, A et al. (2003) ATP causes glomus cell [Ca2+]c increase without corresponding increases in CSN activity. Respir Physiol Neurobiol 138:1-18
Baby, Santhosh M; Roy, Arijit; Mokashi, Anil M et al. (2003) Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1alpha and -1beta in the rat carotid body and glomus cells. Histochem Cell Biol 120:343-52
Lahiri, Sukhamay; Di Giulio, Camillo; Roy, Arijit (2002) Lessons from chronic intermittent and sustained hypoxia at high altitudes. Respir Physiol Neurobiol 130:223-33
Li, Jinqing; Roy, Arijit; Mokashi, Anil et al. (2002) CO-induced K(+) currents in rat glomus cells are insensitive to light unlike carotid body neural discharge and Vo(O(2)). Respir Physiol Neurobiol 131:285-90

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