Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL050827-02
Application #
3369766
Study Section
Special Emphasis Panel (ZHL1 (S2))
Project Start
1994-02-01
Project End
1998-08-31
Budget Start
1994-02-01
Budget End
1994-08-31
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Temple University
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122

  Publications

Sakthivel, R; Zhang, J C; Strickland, D K et al. (2001) Regulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation. J Biol Chem 276:555-62
Ma, K; Simantov, R; Zhang, J C et al. (2000) High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II. J Biol Chem 275:15541-8
Zhang, J C; Claffey, K; Sakthivel, R et al. (2000) Two-chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: partial activity within domain 5. FASEB J 14:2589-600
Zhang, J C; Sakthivel, R; Kniss, D et al. (1998) The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor regulates cell surface plasminogen activator activity on human trophoblast cells. J Biol Chem 273:32273-80
Graham, C H; Fitzpatrick, T E; McCrae, K R (1998) Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway. Blood 91:3300-7
Lin, Y; Harris, R B; Yan, W et al. (1997) High molecular weight kininogen peptides inhibit the formation of kallikrein on endothelial cell surfaces and subsequent urokinase-dependent plasmin formation. Blood 90:690-7
Colman, R W; Pixley, R A; Najamunnisa, S et al. (1997) Binding of high molecular weight kininogen to human endothelial cells is mediated via a site within domains 2 and 3 of the urokinase receptor. J Clin Invest 100:1481-7
Higazi, A A; Mazar, A; Wang, J et al. (1996) Single-chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1. Blood 87:3545-9
Higazi A al-R; Cines, D (1996) Regulation of single chain urokinase by small peptides. Thromb Res 84:243-52
Multhaupt, H A; Gafvels, M E; Kariko, K et al. (1996) Expression of very low density lipoprotein receptor in the vascular wall. Analysis of human tissues by in situ hybridization and immunohistochemistry. Am J Pathol 148:1985-97

Showing the most recent 10 out of 15 publications