Contractile Regulation in Cardiac Muscle

Martyn, Donald L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL051277-03
• Application #: 2029013
• Study Section: Cardiovascular and Pulmonary Research A Study Section (CVA)
• Project Start: 1994-08-01
• Project End: 1999-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Washington
• Department: Engineering (All Types)
• Type: Schools of Medicine
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Martyn, D A; Chase, P B; Regnier, M et al. (2002) A simple model with myofilament compliance predicts activation-dependent crossbridge kinetics in skinned skeletal fibers. Biophys J 83:3425-34

Martyn, D A; Regnier, M; Xu, D et al. (2001) Ca2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle. Biophys J 80:360-70

Regnier, M; Rivera, A J; Chase, P B et al. (1999) Regulation of skeletal muscle tension redevelopment by troponin C constructs with different Ca2+ affinities. Biophys J 76:2664-72

Martyn, D A; Freitag, C J; Chase, P B et al. (1999) Ca2+ and cross-bridge-induced changes in troponin C in skinned skeletal muscle fibers: effects of force inhibition. Biophys J 76:1480-93

Regnier, M; Chase, P B; Martyn, D A (1999) Contractile properties of rabbit psoas muscle fibres inhibited by beryllium fluoride. J Muscle Res Cell Motil 20:425-32

Regnier, M; Martyn, D A; Chase, P B (1998) Calcium regulation of tension redevelopment kinetics with 2-deoxy-ATP or low [ATP] in rabbit skeletal muscle. Biophys J 74:2005-15

Regnier, M; Martyn, D A; Chase, P B (1996) Calmidazolium alters Ca2+ regulation of tension redevelopment rate in skinned skeletal muscle. Biophys J 71:2786-94