Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052138-02
Application #
2229332
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1995-07-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Mukhopadhyay, Sudit S; Leung, Kathryn S; Hicks, M John et al. (2006) Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia. J Cell Biol 175:225-35
Ren, J; Youssoufian, H (2001) Functional analysis of the putative peroxidase domain of FANCA, the Fanconi anemia complementation group A protein. Mol Genet Metab 72:54-60
Holmes, R K; Harutyunyan, K; Shah, M et al. (2001) Correction of cross-linker sensitivity of Fanconi anemia group F cells by CD33-mediated protein transfer. Blood 98:3817-22
Huber, P A; Medhurst, A L; Youssoufian, H et al. (2000) Investigation of Fanconi anemia protein interactions by yeast two-hybrid analysis. Biochem Biophys Res Commun 268:73-7
Wong, J C; Alon, N; Norga, K et al. (2000) Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA. Genomics 67:273-83
Waisfisz, Q; de Winter, J P; Kruyt, F A et al. (1999) A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA. Proc Natl Acad Sci U S A 96:10320-5
Abou-Zahr, F; Bejjani, B; Kruyt, F A et al. (1999) Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome. Am J Med Genet 83:388-91
Youssoufian, H; Gharibyan, V; Qatanani, M (1999) Analysis of epitope-tagged forms of the dyskeratosis congenital protein (dyskerin): identification of a nuclear localization signal. Blood Cells Mol Dis 25:305-9
Abu-Issa, R; Eichele, G; Youssoufian, H (1999) Expression of the Fanconi anemia group A gene (Fanca) during mouse embryogenesis. Blood 94:818-24
Kruyt, F A; Hoshino, T; Liu, J M et al. (1998) Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase. Blood 92:3050-6

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