Retrieval in Medical Image Databases is greatly facilitated by queries which use visual and graphical examples. In such queries, the user points to features of interest in an example image and the database is expected to retrieve other images which have similar features. This proposal seeks to create the capacity for retrieval by shape similarity in an echocardiographic image database. The proposal has three aims.
The first aim i s to create robust shape features. Much of the previous work on shape analysis uses shape features which are invariant to certain image transformations. Unfortunately these features are very susceptible to noise and are not practically useful. A primary aim of this proposal is to seek alternate and more robust shape features. Preliminary work by the investigators and others suggests that there are non-invariant features which satisfy these demands, and the proposal seeks to investigate these in more detail.
The second aim i s to create novel structures and algorithms for indexing these features. Classical indexing techniques, such as indexing trees, are applicable for indexing invariant features. The proposal seeks to extend these techniques substantially for indexing non-invariant shape features. The extension is based on the application of the theory of interval valued arithmetic to indexing. Finally, the proposal seeks to validate the mechanism of retrieval by shape similarity in echocardiography. First, the robustness of the new shape features will be compared to the robustness of old shape features by adding noise to the data. Second, the efficiency of retrieval with the new indexing mechanisms will be measured by simulations and by evaluating the performance for the echocardiographic image database. Lastly, the utility of shape similarity retrieval will be evaluated by measuring the performance of the database to that of expert cardiac radiologists.

Agency
National Institute of Health (NIH)
Institute
National Library of Medicine (NLM)
Type
Research Project (R01)
Project #
1R01LM006911-01
Application #
6031326
Study Section
Biomedical Library and Informatics Review Committee (BLR)
Program Officer
Florance, Valerie
Project Start
2000-06-01
Project End
2003-05-31
Budget Start
2000-06-01
Budget End
2001-05-31
Support Year
1
Fiscal Year
2000
Total Cost
$221,037
Indirect Cost
Name
Yale University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Qian, Xiaoning; Tagare, Hemant D; Fulbright, Robert K et al. (2010) Optimal embedding for shape indexing in medical image databases. Med Image Anal 14:243-54
Qian, Xiaoning; Tagare, Hemant D (2005) Optimal embedding for shape indexing in medical image databases. Med Image Comput Comput Assist Interv 8:377-84
Tao, Zhong; Tagare, Hemant D (2005) Tunneling descent level set segmentation of ultrasound images. Inf Process Med Imaging 19:750-61
Tao, Zhong; Jaffe, C Carl; Tagare, Hemant D (2003) Tunnelling descent: a new algorithm for active contour segmentation of ultrasound images. Inf Process Med Imaging 18:246-57