Abstract

The long-range goal of our research is to understand the neural basis of visual behavior. We will work toward this goal by studying the Limulus visual system. Its retina contains the largest neural network for which a quantitative model exists, and we understand the animal's visual behavior well enough to determine precisely what it sees. our computational studies have yielded remarkable, new insights about how the retinal network encodes important visual information. We will combine theoretical and experimental techniques to investigate what information the eye must send to the brain for the animal to see and how the brain decodes this information.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH049741-08
Application #
2890516
Study Section
Cognitive Functional Neuroscience Review Committee (CFN)
Program Officer
Glanzman, Dennis L
Project Start
1993-04-01
Project End
2000-05-31
Budget Start
1999-06-01
Budget End
2000-05-31
Support Year
8
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Upstate Medical University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210

  Publications

Umino, Yumiko; Solessio, Eduardo; Barlow, Robert B (2008) Speed, spatial, and temporal tuning of rod and cone vision in mouse. J Neurosci 28:189-98
Barlow, R B; Hitt, J M; Dodge, F A (2001) Limulus vision in the marine environment. Biol Bull 200:169-76
Ruta, V J; Dodge, F A; Barlow, R B (1998) Efferent modulation of physiological properties of the Limulus lateral eye. Biol Bull 195:189-90
Stewart, K M; Porcello, D M; McSweeney, M E et al. (1997) Histamine: putative transmitter for lateral inhibition in Limulus eye. Biol Bull 193:203-5
Passaglia, C; Dodge, F; Herzog, E et al. (1997) Deciphering a neural code for vision. Proc Natl Acad Sci U S A 94:12649-54
Passaglia, C L; McSweeney, M E; Stewart, K M et al. (1997) Visual performance of horseshoe crabs: role of underwater lighting. Biol Bull 193:205-7
Herzog, E D; Powers, M K; Barlow Jr, R B (1996) Limulus vision in the ocean day and night: effects of image size and contrast. Vis Neurosci 13:31-41
Passaglia, C L; Dodge, F A; Barlow, R B (1995) Limulus is tuned into its visual environment. Biol Bull 189:213-5
O'Brien, E V; Barlow, R B (1995) Optical imaging of intrinsic signals from the Limulus optic nerve. Biol Bull 189:212-3
Passaglia, C L; Dodge, F A; Barlow Jr, R B (1994) Visual responses in the brain of Limulus. Biol Bull 187:260-1

Showing the most recent 10 out of 11 publications