Neurochemistry of Serotonin System in Suicide Victims

Austin, Mark C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Mental Health (NIMH)
• Type: Research Project (R01)
• Project #: 5R01MH057011-03
• Application #: 6392227
• Study Section: Special Emphasis Panel (ZRG1-BDCN-6 (01))
• Program Officer: Meinecke, Douglas L
• Project Start: 1999-05-01
• Project End: 2003-04-30
• Budget Start: 2001-05-01
• Budget End: 2003-04-30
• Support Year: 3
• Fiscal Year: 2001
• Total Cost: $215,322

Institution

• Name: University of Pittsburgh
• Department: Psychiatry
• Type: Schools of Medicine
• DUNS #: 053785812
• City: Pittsburgh
• State: PA
• Country: United States
• Zip Code: 15213

Publications

Bonkale, W L; Austin, M C (2008) 3,4-Methylenedioxymethamphetamine induces differential regulation of tryptophan hydroxylase 2 protein and mRNA levels in the rat dorsal raphe nucleus. Neuroscience 155:270-6

Bonkale, Willy L; Turecki, Gustavo; Austin, Mark C (2006) Increased tryptophan hydroxylase immunoreactivity in the dorsal raphe nucleus of alcohol-dependent, depressed suicide subjects is restricted to the dorsal subnucleus. Synapse 60:81-5

Iyo, Abiye H; Porter, Bethany; Deneris, Evan S et al. (2005) Regional distribution and cellular localization of the ETS-domain transcription factor, FEV, mRNA in the human postmortem brain. Synapse 57:223-8

Bonkale, Willy L; Murdock, Shayna; Janosky, Janine E et al. (2004) Normal levels of tryptophan hydroxylase immunoreactivity in the dorsal raphe of depressed suicide victims. J Neurochem 88:958-64

Austin, M C; Janosky, J E; Murphy, H A (2003) Increased corticotropin-releasing hormone immunoreactivity in monoamine-containing pontine nuclei of depressed suicide men. Mol Psychiatry 8:324-32

Austin, M C; Whitehead, R E; Edgar, C L et al. (2002) Localized decrease in serotonin transporter-immunoreactive axons in the prefrontal cortex of depressed subjects committing suicide. Neuroscience 114:807-15