There is a paucity of information on late life bipolar disorder. Unlike bipolar disorder in the young, familial factors are less important in the elderly. In fact, available data suggests that elderly bipolar patients are a distinct group. Vascular factors may be of more importance than genetic factors in the development of bipolar disorder in late life. The present proposal is designed to compare neuroanatomical and clinical features of late life bipolar disorder to young bipolar subjects. In addition, we will contrast late life bipolar patients to similar age controls and to late life unipolar subjects drawn from our Clinical Research Center for Depression in the Elderly. This research is likely to be valuable in developing an understanding of the psychobiology of bipolar disorder and could lead to improving diagnosis and management of late life bipolar disorder.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH057027-02
Application #
2883415
Study Section
Mental Disorders of Aging Review Committee (MDA)
Program Officer
Otey, Emeline M
Project Start
1998-03-15
Project End
2003-02-28
Budget Start
1999-03-01
Budget End
2000-02-29
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Duke University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
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