Cognitive neuroscience research has greatly advanced our understanding of the cognitive and neural processes that underlie the successful encoding and retrieval of information. The bulk of this research, however, has been conducted with stimuli intentionally chosen to elicit no emotional responses. But in our daily lives, many experiences are infused with emotional importance and personal significance: We receive a compliment from a coworker, or we witness a car crash. These memories are often powerfully vivid;we can feel transported in time as we re-experience these affect- laden moments.11,19,21,22,41,54,60,113,122 To date, most research examining why memories of emotional events have a different profile than memories of neutral events has focused on influences that are exerted as information is initially learned, 54,69,87,88,119 and our prior cycl of grant funding focused on encoding processes as well. This research has revealed an interesting effect of affective valence: negative events are encoded with more sensory processing and positive information is encoded with more conceptual processing, even when the events are equally high in arousal.69,72,73,74,103,104,105 Although less is known about how affect influences retrieval, many influential models of memory conceive of retrieval as a process during which the processes of encoding are reactivated23,108,174. If true, then affective influences during encoding should have downstream effects on the types of retrieval processes engaged or on the types of retrieval cues that would be most effective. The proposed research addresses this possibility, examining how the affective content of information influences the cognitive and neural processes engaged during memory retrieval, giving particular consideration to the possibility that the processes engaged during retrieval will be influenced by those engaged during encoding.

Public Health Relevance

By addressing core questions with regard to emotion's effects on memory retrieval, the proposed research will provide insight into how memory operates within the emotional context of everyday life. This knowledge is important for a basic research understanding of memory and is relevant to the memory disorders and biases observed in affective disorders such as depression, anxiety, or Post-Traumatic Stress Disorder.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH080833-06
Application #
8473278
Study Section
Cognition and Perception Study Section (CP)
Program Officer
Simmons, Janine M
Project Start
2007-12-01
Project End
2017-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
6
Fiscal Year
2013
Total Cost
$338,040
Indirect Cost
$122,040
Name
Boston College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
045896339
City
Chestnut Hill
State
MA
Country
United States
Zip Code
02467
Ford, Jaclyn H; Morris, John A; Kensinger, Elizabeth A (2014) Neural recruitment and connectivity during emotional memory retrieval across the adult life span. Neurobiol Aging 35:2770-84
Mickley Steinmetz, Katherine R; Waring, Jill D; Kensinger, Elizabeth A (2014) The effect of divided attention on emotion-induced memory narrowing. Cogn Emot 28:881-92
Allard, Eric S; Kensinger, Elizabeth A (2014) Age-related differences in functional connectivity during cognitive emotion regulation. J Gerontol B Psychol Sci Soc Sci 69:852-60
Ford, Jaclyn Hennessey; Morris, John A; Kensinger, Elizabeth A (2014) Effects of emotion and emotional valence on the neural correlates of episodic memory search and elaboration. J Cogn Neurosci 26:825-39
Murray, Brendan D; Kensinger, Elizabeth A (2014) The route to an integrative associative memory is influenced by emotion. PLoS One 9:e82372
Bennion, Kelly A; Ford, Jaclyn H; Murray, Brendan D et al. (2013) Oversimplification in the study of emotional memory. J Int Neuropsychol Soc 19:953-61
Waring, Jill D; Addis, Donna Rose; Kensinger, Elizabeth A (2013) Effects of aging on neural connectivity underlying selective memory for emotional scenes. Neurobiol Aging 34:451-67
Holland, Alisha C; Kensinger, Elizabeth A (2013) The neural correlates of cognitive reappraisal during emotional autobiographical memory recall. J Cogn Neurosci 25:87-108
Holland, Alisha C; Kensinger, Elizabeth A (2013) An fMRI investigation of the cognitive reappraisal of negative memories. Neuropsychologia 51:2389-400
Kensinger, Elizabeth A; Addis, Donna Rose; Atapattu, Ranga K (2011) Amygdala activity at encoding corresponds with memory vividness and with memory for select episodic details. Neuropsychologia 49:663-73

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