Public Health Relevance

Self-control issues are acknowledged as a major public health problem in typical adolescence and young adulthood and a number of psychiatric disorders, such as Attention-Deficit/Hyperactivity Disorder. Behavioral and neuroimaging studies on the processes that lead to the development of self-control will enable us to develop more targeted, age-appropriate interventions to improve self-control. The goal of this project is to study how self-control decisions change with the development of brain regions involved in planned, effortful responding and in brain regions involved in responding to rewards in ADHD and typical development.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
3R01MH091068-03S1
Application #
8842742
Study Section
Child Psychopathology and Developmental Disabilities Study Section (CPDD)
Program Officer
Friedman-Hill, Stacia
Project Start
2012-08-15
Project End
2016-05-31
Budget Start
2014-06-02
Budget End
2015-05-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of California Davis
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Davis
State
CA
Country
United States
Zip Code
95618
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Holroyd, Clay B; McClure, Samuel M (2015) Hierarchical control over effortful behavior by rodent medial frontal cortex: A computational model. Psychol Rev 122:54-83
Romens, Sarah E; Casement, Melynda D; McAloon, Rose et al. (2015) Adolescent girls' neural response to reward mediates the relation between childhood financial disadvantage and depression. J Child Psychol Psychiatry 56:1177-84
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Fassbender, Catherine; Houde, Sebastien; Silver-Balbus, Shayla et al. (2014) The decimal effect: behavioral and neural bases for a novel influence on intertemporal choice in healthy individuals and in ADHD. J Cogn Neurosci 26:2455-68
Rutledge, Kyle J; van den Bos, Wouter; McClure, Samuel M et al. (2012) Training cognition in ADHD: current findings, borrowed concepts, and future directions. Neurotherapeutics 9:542-58