The purpose of this randomized clinical trial is to test a 12-month multi-component health promotion intervention with home-based family caregivers of persons with Alzheimer's Disease and other related dementias.
Specific aims are to: 1) Test the primary hypothesis: The Enhancing Physical Activity treatment intervention will be more effective in increasing caregiver lifestyle physical activity than the Standard Care Intervention;2) Test secondary hypotheses: The Enhancing Physical Activity treatment intervention will be more effective than the Standard Care Intervention in improving the following caregiver secondary outcomes: mental health, physical health and physical function, and 3) Evaluate the process of implementing a lifestyle physical activity intervention with family caregivers. The Standard Care Intervention focuses on well- established care-related education and support needs. The Enhancing Physical Activity treatment intervention focuses on two areas: increasing lifestyle physical activity and addressing well-established care-related concerns that are likely to interfere with increasing physical activity. A total of 190 middle-age to older community-based primary caregivers of persons with Alzheimer's disease or other related dementias who report some to moderate strain with caregiving activities will be randomly assigned to either the Enhancing Physical Activity or Standard Care Intervention. Data will be collected at baseline, 3, 6, 9,12 and 18 months and include self-report and direct observational methods. Data will be analyzed by using repeated measures models using the generalized estimating equation approach. Family caregivers are a stressed population who experience changes in their mental and physical health. However, effect sizes have been minimal for interventions designed to only affect caregiver mental health. No study known to us, has tested the added value of physical activity adoption in conjunction with more traditional caregiver support and skill building. Study findings will enable us to evaluate the behavioral, physical, and health-related quality of life effects achieved by the combined intervention;and will add knowledge about the most effective ways of intervening with family caregivers and other chronically stressed middle-age and older adult populations.
|Pool, Lindsay R; Weuve, Jennifer; Wilson, Robert S et al. (2016) Occupational cognitive requirements and late-life cognitive aging. Neurology 86:1386-92|
|Farran, Carol J; Etkin, Caryn D; Eisenstein, Amy et al. (2016) Effect of Moderate to Vigorous Physical Activity Intervention on Improving Dementia Family Caregiver Physical Function: A Randomized Controlled Trial. J Alzheimers Dis Parkinsonism 6:|
|Farran, Carol J; Paun, Olimpia; Cothran, Fawn et al. (2016) Impact of an Individualized Physical Activity Intervention on Improving Mental Health Outcomes in Family Caregivers of Persons with Dementia: A Randomized Controlled Trial. AIMS Med Sci 3:15-31|
|Cothran, Fawn A; Paun, Olimpia; Farran, Carol J et al. (2016) Racial Differences in Program Evaluation of a Lifestyle Physical Activity Randomized Controlled Trial. West J Nurs Res 38:1264-81|
|Weuve, Jennifer; Hebert, Liesi E; Scherr, Paul A et al. (2015) Prevalence of Alzheimer disease in US states. Epidemiology 26:e4-6|
|Aggarwal, Neelum T; Clark, Cari J; Beck, Todd L et al. (2014) Perceived stress is associated with subclinical cerebrovascular disease in older adults. Am J Geriatr Psychiatry 22:53-62|
|Etkin, Caryn D; Farran, Carol J; Barnes, Lisa L et al. (2012) Recruitment and enrollment of caregivers for a lifestyle physical activity clinical trial. Res Nurs Health 35:70-81|
|Farran, Carol J; Etkin, Caryn D; McCann, Judith J et al. (2011) Role of technology in supporting quality control and treatment fidelity in a family caregiver clinical trial. West J Nurs Res 33:953-78|
|Wilson, R S; Hoganson, G M; Rajan, K B et al. (2010) Temporal course of depressive symptoms during the development of Alzheimer disease. Neurology 75:21-6|
|Wilson, R S; Barnes, L L; Aggarwal, N T et al. (2010) Cognitive activity and the cognitive morbidity of Alzheimer disease. Neurology 75:990-6|
Showing the most recent 10 out of 13 publications