Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS015963-16
Application #
2262927
Study Section
Neurology C Study Section (NEUC)
Project Start
1980-01-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Physiology
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Yi, B A; Minor Jr, D L; Lin, Y F et al. (2001) Controlling potassium channel activities: Interplay between the membrane and intracellular factors. Proc Natl Acad Sci U S A 98:11016-23
Schwappach, B; Zerangue, N; Jan, Y N et al. (2000) Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+ channel with an ABC transporter. Neuron 26:155-67
Zerangue, N; Jan, Y N; Jan, L Y (2000) An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1. Proc Natl Acad Sci U S A 97:3591-5
Chuang, H H; Yu, M; Jan, Y N et al. (1998) Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channels. Proc Natl Acad Sci U S A 95:11727-32
Jan, L Y; Jan, Y N (1997) Voltage-gated and inwardly rectifying potassium channels. J Physiol 505 ( Pt 2):267-82
Jan, L Y; Jan, Y N (1997) Cloned potassium channels from eukaryotes and prokaryotes. Annu Rev Neurosci 20:91-123
Lopez, G A; Jan, Y N; Jan, L Y (1991) Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in Shaker K+ channels. Neuron 7:327-36
Schwarz, T L; Papazian, D M; Carretto, R C et al. (1990) Immunological characterization of K+ channel components from the Shaker locus and differential distribution of splicing variants in Drosophila. Neuron 4:119-27
Royden, C S; Pirrotta, V; Jan, L Y (1987) The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12. Cell 51:165-73
Tempel, B L; Papazian, D M; Schwarz, T L et al. (1987) Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science 237:770-5

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