Abstract

This study will investigate changes in neuropsychological and psychosocial function in epileptic adults and children over time. One hundred adults, already tested with the neuropsychological battery for epilepsy and the Washington Psychosocial Seizure Inventory, will be re-tested five years from original testing. Two hundred and thirty children will be tested with age-appropriate version of the neuropsychological battery on two occasions, separated by two and one-half years; in 70 of these, original testing has been done and both two and one-half year and five year testing will be done. Standardization will be done by testing a control group of non-epileptic children. Data on longitudinal psychosocial function in children will be obtained by administration of an age-modified psychosocial interview on two occasions separated by two and a half years. Correlation of change in neuropsychological and psychosocial functions with seizure type, seizure frequency, age at onset, duration of seizure disorder and medication will be sought.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS017277-05
Application #
3397464
Study Section
Human Development and Aging Subcommittee 1 (HUD)
Project Start
1981-07-01
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1987-06-30
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Dodrill, C B; Wilensky, A J (1992) Neuropsychological abilities before and after 5 years of stable antiepileptic drug therapy. Epilepsia 33:327-34
Batzel, L W; Dodrill, C B; Dubinsky, B L et al. (1991) An objective method for the assessment of psychosocial problems in adolescents with epilepsy. Epilepsia 32:202-11
Dodrill, C B; Temkin, N R (1989) Motor speed is a contaminating factor in evaluating the ""cognitive"" effects of phenytoin. Epilepsia 30:453-7
Klusman, L E; Cripe, L I; Dodrill, C B (1989) Analysis of errors on the Trail Making Test. Percept Mot Skills 68:1199-204
Wilkus, R J; Dodrill, C B (1989) Factors affecting the outcome of MMPI and neuropsychological assessments of psychogenic and epileptic seizure patients. Epilepsia 30:339-47
Dodrill, C B (1988) Effects of antiepileptic drugs on abilities. J Clin Psychiatry 49 Suppl:31-4
Dodrill, C B; Warner, M H (1988) Further studies of the Wonderlic Personnel Test as a brief measure of intelligence. J Consult Clin Psychol 56:145-7
Dodrill, C B; Batzel, L W; Wilensky, A J et al. (1987) The role of psychosocial and financial factors in medication noncompliance in epilepsy. Int J Psychiatry Med 17:143-54
Dodrill, C B; Batzel, L W (1986) Interictal behavioral features of patients with epilepsy. Epilepsia 27 Suppl 2:S64-76
Dodrill, C B (1986) Correlates of generalized tonic-clonic seizures with intellectual, neuropsychological, emotional, and social function in patients with epilepsy. Epilepsia 27:399-411

Showing the most recent 10 out of 17 publications