Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS017620-15
Application #
2263233
Study Section
Physiology Study Section (PHY)
Project Start
1981-09-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Physiology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Baylor, Stephen M; Hollingworth, Stephen (2007) Simulation of Ca2+ movements within the sarcomere of fast-twitch mouse fibers stimulated by action potentials. J Gen Physiol 130:283-302
Hollingworth, Stephen; Chandler, W Knox; Baylor, Stephen M (2006) Effects of tetracaine on voltage-activated calcium sparks in frog intact skeletal muscle fibers. J Gen Physiol 127:291-307
Kang, Myungsa; Lisk, Godfrey; Hollingworth, Stephen et al. (2005) Malaria parasites are rapidly killed by dantrolene derivatives specific for the plasmodial surface anion channel. Mol Pharmacol 68:34-40
Baylor, Stephen M (2005) Calcium sparks in skeletal muscle fibers. Cell Calcium 37:513-30
Chandler, W K; Hollingworth, S; Baylor, S M (2003) Simulation of calcium sparks in cut skeletal muscle fibers of the frog. J Gen Physiol 121:311-24
Baylor, S M; Hollingworth, S (2003) Sarcoplasmic reticulum calcium release compared in slow-twitch and fast-twitch fibres of mouse muscle. J Physiol 551:125-38
Cheung, A; Dantzig, J A; Hollingworth, S et al. (2002) A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol 4:83-8
Baylor, S M; Hollingworth, S; Chandler, W K (2002) Comparison of simulated and measured calcium sparks in intact skeletal muscle fibers of the frog. J Gen Physiol 120:349-68
Hollingworth, S; Peet, J; Chandler, W K et al. (2001) Calcium sparks in intact skeletal muscle fibers of the frog. J Gen Physiol 118:653-78
Baylor, S M; Hollingworth, S (1998) Model of sarcomeric Ca2+ movements, including ATP Ca2+ binding and diffusion, during activation of frog skeletal muscle. J Gen Physiol 112:297-316

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