Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS018309-17S1
Application #
2446623
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1992-06-29
Project End
2000-01-31
Budget Start
1997-02-01
Budget End
1998-01-31
Support Year
17
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Nishimura, Masataka; Casanova, J R; Swann, John W (2017) The Impact of Electrographic Seizures on Developing Hippocampal Dendrites Is Calcineurin Dependent. eNeuro 4:
Frost Jr, James D; Le, John T; Lee, Chong L et al. (2015) Vigabatrin therapy implicates neocortical high frequency oscillations in an animal model of infantile spasms. Neurobiol Dis 82:1-11
Casanova, J R; Nishimura, Masataka; Swann, John W (2014) The effects of early-life seizures on hippocampal dendrite development and later-life learning and memory. Brain Res Bull 103:39-48
Lugo, Joaquin N; Swann, John W; Anderson, Anne E (2014) Early-life seizures result in deficits in social behavior and learning. Exp Neurol 256:74-80
Weston, Matthew C; Chen, Hongmei; Swann, John W (2014) Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures. Front Mol Neurosci 7:1
Casanova, J R; Nishimura, M; Le, J et al. (2013) Rapid hippocampal network adaptation to recurring synchronous activity--a role for calcineurin. Eur J Neurosci 38:3115-27
Weston, Matthew C; Chen, Hongmei; Swann, John W (2012) Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission. J Neurosci 32:11441-52
Frost Jr, James D; Lee, Chong L; Le, John T et al. (2012) Interictal high frequency oscillations in an animal model of infantile spasms. Neurobiol Dis 46:377-88
Nishimura, Masataka; Gu, Xue; Swann, John W (2011) Seizures in early life suppress hippocampal dendrite growth while impairing spatial learning. Neurobiol Dis 44:205-14
Frost Jr, James D; Lee, Chong L; Hrachovy, Richard A et al. (2011) High frequency EEG activity associated with ictal events in an animal model of infantile spasms. Epilepsia 52:53-62

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