Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS035120-01
Application #
2274449
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1996-05-01
Project End
2000-02-29
Budget Start
1996-05-01
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Kung, Mei-Ping; Choi, Seok-Rye; Hou, Catherine et al. (2004) Selective binding of 2-[125I]iodo-nisoxetine to norepinephrine transporters in the brain. Nucl Med Biol 31:533-41
Acton, P D; Choi, S R; Hou, C et al. (2001) Quantification of serotonin transporters in nonhuman primates using [(123)I]ADAM and SPECT. J Nucl Med 42:1556-62
Choi, S R; Hou, C; Oya, S et al. (2000) Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain. Synapse 38:403-12
Oya, S; Choi, S R; Hou, C et al. (2000) 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand. Nucl Med Biol 27:249-54
Zhuang, Z; Choi, S; Hou, C et al. (2000) A novel serotonin transporter ligand: (5-iodo-2-(2-dimethylaminomethylphenoxy)-benzyl alcohol. Nucl Med Biol 27:169-75
Acton, P D; Mu, M; Plossl, K et al. (1999) Single-photon emission tomography imaging of serotonin transporters in the nonhuman primate brain with [(123)I]ODAM. Eur J Nucl Med 26:1359-62
Kung, M P; Hou, C; Oya, S et al. (1999) Characterization of [(123)I]IDAM as a novel single-photon emission tomography tracer for serotonin transporters. Eur J Nucl Med 26:844-53
Oya, S; Kung, M P; Acton, P D et al. (1999) A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol. J Med Chem 42:333-5
Acton, P D; Kung, M P; Mu, M et al. (1999) Single-photon emission tomography imaging of serotonin transporters in the non-human primate brain with the selective radioligand [(123)I]IDAM. Eur J Nucl Med 26:854-61
Zhuang, Z P; Kung, M P; Mu, M et al. (1998) Isoindol-1-one analogues of 4-(2'-methoxyphenyl)-1-[2'-[N-(2""-pyridyl)-p-iodobenzamido]ethyl]pipera zine (p-MPPI) as 5-HT1A receptor ligands. J Med Chem 41:157-66