Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS035549-01
Application #
2274813
Study Section
Physiology Study Section (PHY)
Project Start
1996-09-15
Project End
2000-07-31
Budget Start
1996-09-15
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Palty, Raz; Fu, Zhu; Isacoff, Ehud Y (2017) Sequential Steps of CRAC Channel Activation. Cell Rep 19:1929-1939
Chen, Yushu; Bharill, Shashank; Altun, Zeynep et al. (2016) Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins. Mol Biol Cell 27:1272-85
Chen, Yushu; Bharill, Shashank; O'Hagan, Robert et al. (2016) MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans. G3 (Bethesda) 6:1121-30
Palty, Raz; Isacoff, Ehud Y (2016) Cooperative Binding of Stromal Interaction Molecule 1 (STIM1) to the N and C Termini of Calcium Release-activated Calcium Modulator 1 (Orai1). J Biol Chem 291:334-41
Levitz, Joshua; Royal, Perrine; Comoglio, Yannick et al. (2016) Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels. Proc Natl Acad Sci U S A 113:4194-9
Berger, Thomas K; Isacoff, Ehud Y (2015) Fluorescent labeling for patch-clamp fluorometry (PCF) measurements of real-time protein motion in ion channels. Methods Mol Biol 1266:93-106
Palty, Raz; Stanley, Cherise; Isacoff, Ehud Y (2015) Critical role for Orai1 C-terminal domain and TM4 in CRAC channel gating. Cell Res 25:963-80
Chen, Yushu; Bharill, Shashank; Isacoff, Ehud Y et al. (2015) Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans. Proc Natl Acad Sci U S A 112:11690-5
Mony, Laetitia; Berger, Thomas K; Isacoff, Ehud Y (2015) A specialized molecular motion opens the Hv1 voltage-gated proton channel. Nat Struct Mol Biol 22:283-290
Comoglio, Yannick; Levitz, Joshua; Kienzler, Michael A et al. (2014) Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid. Proc Natl Acad Sci U S A 111:13547-52

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