This proposed pilot research is the first step in a series of planned investigations concerning the clinically documented problem of managing pain in alcoholic patients. The goal of this initial work is to document higher pain sensitivity among alcoholics in a controlled laboratory setting at baseline and in the presence of peripherally acting local anesthesia and centrally acting nitrous oxide. Alcoholic subjects will be clustered on severity of disease, time since withdrawal from alcohol, and stait anxiety. All subjects will have self-reported histories of intra-treatment pain control problems in dental settings. Controls will be matched on age and race. Intra- and inter-group comparisons will be made following electrical tooth stimulation at pain stimulus detection, pain threshold, and pain tolerance.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Small Research Grants (R03)
Project #
1R03AA009154-01
Application #
2045379
Study Section
Clinical and Treatment Subcommittee (ALCP)
Project Start
1992-01-01
Project End
1993-12-31
Budget Start
1992-01-01
Budget End
1992-12-31
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Washington
Department
Dentistry
Type
Schools of Dentistry
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Fiset, L; Leroux, B; Rothen, M et al. (1997) Pain control in recovering alcoholics: effects of local anesthesia. J Stud Alcohol 58:291-6