Human granulocytic ehrlichiosis (HGE) and human monocytic ehrlichiosis (HME) are emerging tick-borne disease in the U.S. Annual incidence of both disease is increasing, with more than 600 cases of human ehrlichiosis reported in the last ten years. The purpose of this study is to detect the presence and distribution of the HGE agent and related ehrlichial pathogens in New York State. Specifically, the applicant will evaluate the utility of canine serology to assess risk for HGE in an endemic area, 2) measure canine seroprevalence in areas where few or no cases of HGE are reported, 3) test Ixodes scapularis and Amblyomma americanum for the presence of Ehrlichia species and related pathogens, and 4) establish a canine serum bank and a tick depository for future retrospective studies on emerging tick-borne diseases in the region.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Small Research Grants (R03)
Project #
5R03AI042125-03
Application #
6163932
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Baker, Phillip J
Project Start
1998-03-01
Project End
2001-02-28
Budget Start
2000-03-01
Budget End
2001-02-28
Support Year
3
Fiscal Year
2000
Total Cost
$73,798
Indirect Cost
Name
Fordham University
Department
Biology
Type
Other Domestic Higher Education
DUNS #
071011019
City
Bronx
State
NY
Country
United States
Zip Code
10458
Daniels, Thomas J; Battaly, Gertrude R; Liveris, Dionysios et al. (2002) Avian reservoirs of the agent of human granulocytic ehrlichiosis? Emerg Infect Dis 8:1524-5
Gern, L; Falco, R C (2000) Lyme disease. Rev Sci Tech 19:121-35