Contrary to current """"""""neural scrambling"""""""" hypotheses for human amblyopia, I propose that much of the perceptual scrambling seen by amblyopes may be attributed to neural undersampling in the visual system. Using interferometric and video display techniques, I will examine aliasing in amblyopia. I will adopt experimental protocols that have been tested extensively on normals. This proposal is an important pilot for a subsequent """"""""FIRST AWARD' application.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Research Grants (R03)
Project #
1R03EY007638-01
Application #
3426427
Study Section
Vision Research and Training Committee (VSN)
Project Start
1988-04-01
Project End
1990-03-31
Budget Start
1988-04-01
Budget End
1990-03-31
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Indiana University Bloomington
Department
Type
Schools of Optometry/Opht Tech
DUNS #
006046700
City
Bloomington
State
IN
Country
United States
Zip Code
47402
Thibos, L N; Bradley, A (1993) New methods for discriminating neural and optical losses of vision. Optom Vis Sci 70:279-87
Ye, M; Bradley, A; Thibos, L N et al. (1992) The effect of pupil size on chromostereopsis and chromatic diplopia: interaction between the Stiles-Crawford effect and chromatic aberrations. Vision Res 32:2121-8
Bradley, A (1992) Glenn A. Fry Award Lecture 1991: perceptual manifestations of imperfect optics in the human eye: attempts to correct for ocular chromatic aberration. Optom Vis Sci 69:515-21
Bradley, A; Thomas, T; Kalaher, M et al. (1991) Effects of spherical and astigmatic defocus on acuity and contrast sensitivity: a comparison of three clinical charts. Optom Vis Sci 68:418-26
Bradley, A; Zhang, X X; Thibos, L N (1991) Achromatizing the human eye. Optom Vis Sci 68:608-16
Ye, M; Bradley, A; Thibos, L N et al. (1991) Interocular differences in transverse chromatic aberration determine chromostereopsis for small pupils. Vision Res 31:1787-96
Bradley, A; Hook, J; Haeseker, J (1991) A comparison of clinical acuity and contrast sensitivity charts: effect of uncorrected myopia. Ophthalmic Physiol Opt 11:218-26
Geddes, L A; Patel, B J; Bradley, A (1990) Comparison of Snellen and interferometer visual acuity in an aging noncataractous population. Optom Vis Sci 67:361-5
Bradley, A; Thibos, L; Still, D (1990) Visual acuity measured with clinical Maxwellian-view systems: effects of beam entry location. Optom Vis Sci 67:811-7
Applegate, R A; Bradley, A; van Heuven, W A (1990) Entoptic visualization of the retinal vasculature near fixation. Invest Ophthalmol Vis Sci 31:2088-98