The primary objective of this R03 is to examine whether adolescent exposure to IPV increases risk of obesity in young adulthood and whether depressive symptoms, health behaviors or C-reactive protein, a marker of inflammation, mediate this relationship. Our central hypothesis is that IPV exposure in adolescence leads to increased adiposity (body mass and waist circumference) from adolescence to adulthood. We will test this hypothesis using data from the National Longitudinal Study of Adolescent Health. Among the 10,120 respondents who participated in all 4 waves of data collection, we will use structural equation modeling to examine the relationship between IPV and adiposity and whether this relationship is mediated by depressive symptoms, weight promoting health behaviors, and inflammation. We will also explore whether these direct and indirect relationships differ by race/ethnicity, sex, prior exposure to child maltreatment, and characteristics of the relationship, namely whether the violence is bi-directional (both partners use violence against the other) or uni-directional. This project supports our long-term goal of contributing evidence on the mechanisms linking early violence exposure to chronic disease in adulthood to highlight at risk populations and points of intervention at which health disparities may be mitigated.

Public Health Relevance

The proposed study has high public health relevance as it will yield important information about the pathways by which intimate partner violence (IPV) may lead to obesity. IPV and obesity are both major public health problems characterized by disparities that are apparent in adolescence. Knowledge of their relationship could inform cross-cutting upstream interventions geared toward violence and obesity prevention.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Small Research Grants (R03)
Project #
5R03HD068045-02
Application #
8431742
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Maholmes, Valerie
Project Start
2012-02-20
Project End
2015-01-31
Budget Start
2013-02-01
Budget End
2015-01-31
Support Year
2
Fiscal Year
2013
Total Cost
$72,124
Indirect Cost
$24,674
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Suglia, Shakira F; Clark, Cari J; Boynton-Jarrett, Renée et al. (2014) Child maltreatment and hypertension in young adulthood. BMC Public Health 14:1149
Clark, Cari Jo; Spencer, Rachael A; Everson-Rose, Susan A et al. (2014) Dating violence, childhood maltreatment, and BMI from adolescence to young adulthood. Pediatrics 134:678-85
Clark, Cari Jo; Everson-Rose, Susan A; Alonso, Alvaro et al. (2014) Effect of partner violence in adolescence and young adulthood on blood pressure and incident hypertension. PLoS One 9:e92204
Garcia, Lorena; Qi, Lihong; Rasor, Marianne et al. (2014) The relationship of violence and traumatic stress to changes in weight and waist circumference: longitudinal analyses from the study of women's health across the nation. J Interpers Violence 29:1459-76
Clark, Cari Jo; Alonso, Alvaro; Spencer, Rachael A et al. (2014) Predicted long-term cardiovascular risk among young adults in the national longitudinal study of adolescent health. Am J Public Health 104:e108-15
Suglia, Shakira F; Clark, Cari J; Gary-Webb, Tiffany L (2013) Adolescent obesity, change in weight status, and hypertension: racial/ethnic variations. Hypertension 61:290-5