The Tenth and Eleventh International Symposia on Neurobiology &Neuroendocrinology Aging will be held in Bregenz, Austria July 25-30, 2010 and in July 2012. The purpose of these meetings is to bring together a group of investigators who made recent significant advances in the study of mechanisms of aging, with particular emphasis on CNS aging, neuroprotection and treatment of neurodegenerative disease. Specific topics will include the roles of IGF-1 in the brain, shc proteins in endothelial function, mitochondrial regulator proteins, and oxidative stress and the neuromuscular junction. Two lectures will specifically address recent advances in understanding the role of reproductive hormones in aging. Lectures dealing with the mechanisms of aging will also include presentation of new data on the relationship of aging to stress resistance from an evolutionary proteomic adaptation perspective. Discussion of mechanisms specifically related to aging of the CNS will include the roles hypothalamic hormones in dementia, stress-induced retardation of Alzheimer's disease pathology and a therapeutic approach to improve cognition in Alzheimer's disease patients. Lectures about neuroprotective mechanisms include neurodegenerative mechanisms common from worm to man and neurobiology in extreme longevity. We purposely include a wide range of topics and assemble a group of scientists that may not normally attend the same meeting. The format of the meeting is modeled after Gordon Research Conferences and encourages formal and informal discussions of the material presented. Proceedings will be published as a special issue of Experimental Gerontology within approximately six months after the Symposium. Participation of junior investigators, including graduate students and post-doctoral fellows is strongly encouraged and this proposal seeks funds for providing stipends to those US participants who are in training or are in junior faculty positions and who are planning to present their findings in the poster session. We are also seeking partial support for the expenses of invited speakers from the United States.

Public Health Relevance

This proposal requests support of two symposia specifically related to aging. The Tenth and Eleventh Symposia on Neurobiology and Neuroendocrinology will be held July 2010 and July 2012. These meetings focus on mechanisms of aging with an emphasis on the central nervous system including both neuronal and hormonal aspects in addition to age-related disease.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Conference (R13)
Project #
5R13AG035543-02
Application #
7940841
Study Section
National Institute on Aging Initial Review Group (NIA)
Program Officer
Finkelstein, David B
Project Start
2009-09-30
Project End
2012-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
2
Fiscal Year
2010
Total Cost
$1
Indirect Cost
Name
University of North Dakota
Department
Pharmacology
Type
Schools of Medicine
DUNS #
102280781
City
Grand Forks
State
ND
Country
United States
Zip Code
58202