Primary central nervous system lymphoma (PCNSL) is an extranodal variant of non- Hodgkin lymphoma (NHL) that is confined to the nervous system. The diagnostic and therapeutic approaches to PCNSL are different from those that are applied to other forms of NHL or to other brain cancers. The International Primary Central Nervous System Lymphoma Collaborative Group (IPCG) consists of specialists from multiple countries and disciplines dedicated to the study of PCNSL. The IPCG holds an annual scientific conference at the American Society of Hematology meeting in which various research topics related to PCNSL are discussed. An international expert on the topic under discussion is selected each year by an executive committee to chair the scientific conference. These meetings have led to multiple collaborative projects that have impacted the field and that have been published in the peer-reviewed literature. The annual IPCG meeting is a critical forum for generating new ideas and approaches to this unique form of brain cancer.

Public Health Relevance

The International Primary Central Nervous System Lymphoma (PCNSL) Collaborative Group (IPCG) holds an annual scientific conference each year to review research progress and to generate new ideas on PCNSL, a type of non-Hodgkin lymphoma in the brain. The annual conference has been very successful in stimulating international collaboration among the many different specialists involved in the treatment of this type of lymphoma. These collaborations have led to clinical trials and new tools to study outcomes in this group of patients.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Conference (R13)
Project #
2R13CA124293-06A1
Application #
8399749
Study Section
Special Emphasis Panel (ZCA1-PCRB-G (M1))
Program Officer
Merritt, William D
Project Start
2006-09-01
Project End
2013-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
6
Fiscal Year
2012
Total Cost
$7,500
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Han, Catherine H; Batchelor, Tracy T (2017) Primary Central Nervous System Lymphoma. Continuum (Minneap Minn) 23:1601-1618
Kasenda, B; Ferreri, A J M; Marturano, E et al. (2015) First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)--a systematic review and individual patient data meta-analysis. Ann Oncol 26:1305-13
Batchelor, Tracy T; Reardon, David A; de Groot, John F et al. (2014) Antiangiogenic therapy for glioblastoma: current status and future prospects. Clin Cancer Res 20:5612-9
Flannick, Jason; Thorleifsson, Gudmar; Beer, Nicola L et al. (2014) Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nat Genet 46:357-63
Ponzoni, M; Issa, S; Batchelor, T T et al. (2014) Beyond high-dose methotrexate and brain radiotherapy: novel targets and agents for primary CNS lymphoma. Ann Oncol 25:316-22
Taylor, Jennie W; Flanagan, Eoin P; O'Neill, Brian P et al. (2013) Primary leptomeningeal lymphoma: International Primary CNS Lymphoma Collaborative Group report. Neurology 81:1690-6
Ferreri, Andrés J M; Zucca, Emanuele; Armitage, James et al. (2013) Ten years of international primary CNS lymphoma collaborative group studies. J Clin Oncol 31:3444-5
Abla, Oussama; Weitzman, Sheila; Blay, Jean-Yves et al. (2011) Primary CNS lymphoma in children and adolescents: a descriptive analysis from the International Primary CNS Lymphoma Collaborative Group (IPCG). Clin Cancer Res 17:346-52
Patrij, Katrin; Reiser, Marcel; Wätzel, Luise et al. (2011) Isolated central nervous system relapse of systemic lymphoma (SCNSL): clinical features and outcome of a retrospective analysis. Ger Med Sci 9:Doc11
Chan, Chi-Chao; Rubenstein, James L; Coupland, Sarah E et al. (2011) Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium. Oncologist 16:1589-99

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