This application requests support for programming of the Division of Chemical Toxicology of the American Chemical Society (ACS) at its 244th National Meeting and Exposition in Philadelphia, PA from Sunday, August 19, 2012 to Wednesday, August 22, 2012. A unique feature of this ACS meeting is the broad theme of the entire meeting, "Materials for Health and Medicine", which aligns highlighted events across the programming of all ACS divisions. The mission of the ACS Division of Chemical Toxicology is to promote the understanding of chemical mechanisms that contribute to disease processes and the toxicity of environmental agents, biomaterials, drugs and endogenous chemicals. The Division integrates work in chemistry, chemical biology, structural biology, toxicology, environmental health sciences and disease mechanisms. The global theme "Materials for Health and Medicine" aligns closely with the core focus areas of the Division of Chemical Toxicology and thus provides a backdrop that reinforces programming in the Division and related content particularly for students and postdoctoral fellows. Three interrelated symposia are planned around the central theme "Human Exposure and Toxic Responses to Biomaterials" and include invited talks by a diverse group of leading established and up-and-coming scientists. The two symposia for which support is requested have especially strong relevance to the mission of the NIEHS. The first (Symposium #2) is entitled "Genome Instability" and addresses molecular mechanisms by which electrophiles and reactive oxygen species cause lesions and mutations to DNA and the resulting repair processes. The second (Symposium #3) is entitled "Harnessing Nanotechnology for Human Health and Environment" and focuses on the emerging field of nanotechnology and health implications for such engineered materials (i.e., nanotoxicology). A proffered paper session and a Young Investigators Symposium offer opportunities for young scientists in training to present their primary contributions and receive critical feedback from senior experts. Other highlights are a keynote awards symposium and a professional development workshop. Overall, the ACS TOXI meeting is designed to disseminate current information regarding toxicants and disease and provide young scientists with a rich training environment.

Public Health Relevance

Effective prevention and treatment of environmentally-related diseases require an understanding of underlying mechanisms that link environmental exposures to disease mechanisms. This meeting of the Division of Chemical Toxicology of the American Chemical Society will explore the chemical mechanisms for disease processes including cancer;specifically, the sponsored symposia will feature cutting edge research on the impact of biomaterials (nanotechnology and nanotoxicology), environmental agents, drugs and endogenous compounds on human health and disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Conference (R13)
Project #
1R13ES022137-01
Application #
8399340
Study Section
Special Emphasis Panel (ZES1-JAB-D (C))
Program Officer
Shaughnessy, Daniel
Project Start
2012-08-01
Project End
2013-07-31
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
1
Fiscal Year
2012
Total Cost
$8,000
Indirect Cost
Name
University of Iowa
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242