The MBL Physiology Course, founded in 1892 and one of the oldest continually running biology courses in the world, is an intensive seven-week laboratory course for graduate students and post-doctoral researchers. The course is dedicated to educating and expanding the diversity of the next generation of biologists through hands-on interdisciplinary research and mentoring. To achieve this, the Physiology Course brings together faculty and students from across the biological and physical sciences, including cell and evolutionary biologists, physicists, engineers, and computer scientists, to create a unique training environment that mixes cell biology with the newest tools and quantitative approaches needed to tackle fundamental biological problems. Students attend lectures by leading scientists in the morning, but the emphasis is on afternoons and evenings in the laboratory, where students ?learn by doing,? with an emphasis on collaboration, the joy of discovery, and the exploration of tools of modern quantitative cell biology. There is no other environment in which such interdisciplinary students and faculty are brought together for 6 days/week and 15 hrs/day to focus on generating new knowledge. The Physiology course also provides mentoring and career guidance to young scientists, creating professional networks that persist long after the course is over. Our new recruitment strategies and faculty training initiatives will ensure that the most promising students from a wide range of ethnic and educational backgrounds are drawn into the course, supported irrespective of their level of financial need or the contributions from their home institution, and mentored appropriately to reach their scientific and career goals. Our goal is to launch the next generation of cell biologists, scientists from diverse backgrounds and perspectives who have the vision and courage to take on the most important challenges and big questions in the field.

Public Health Relevance

The Physiology Course will promote scientific training and interdisciplinary approaches to research by bringing together trainees and faculty in the biological sciences with those in the physical, computational and engineering sciences, engaging students through hands-on laboratory research on cutting-edge interdisciplinary problems, challenging students to think creatively, and helping students develop a fearlessness about science. In the process, students will establish professional networks amongst the student and faculty participants, as well as with the broader MBL community, to support and enhance their future careers and promote a stronger and more interactive biomedical research enterprise. Finally, the Physiology course will provide training and mentoring to a highly diverse group of students, including young scientists from a wide variety of home institutions, socio-economic and ethnic backgrounds by a) partnering with MBL to recruit, support and mentor diverse students; and b) providing financial assistance and a need-blind admission process.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Conference (R13)
Project #
2R13GM085967-15
Application #
9837990
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Ainsztein, Alexandra M
Project Start
2004-09-20
Project End
2021-05-31
Budget Start
2019-06-11
Budget End
2021-05-31
Support Year
15
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Marine Biological Laboratory
Department
Type
DUNS #
001933779
City
Woods Hole
State
MA
Country
United States
Zip Code
02543
Blauch, Lucas R; Gai, Ya; Khor, Jian Wei et al. (2017) Microfluidic guillotine for single-cell wound repair studies. Proc Natl Acad Sci U S A 114:7283-7288
Mohapatra, Lishibanya; Lagny, Thibaut J; Harbage, David et al. (2017) The Limiting-Pool Mechanism Fails to Control the Size of Multiple Organelles. Cell Syst 4:559-567.e14
Swaminathan, Vinay; Kalappurakkal, Joseph Mathew; Mehta, Shalin B et al. (2017) Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions. Proc Natl Acad Sci U S A 114:10648-10653
Mark Welch, Jessica L; Rossetti, Blair J; Rieken, Christopher W et al. (2016) Biogeography of a human oral microbiome at the micron scale. Proc Natl Acad Sci U S A 113:E791-800
Cekan, Pavol; Hasegawa, Keisuke; Pan, Yu et al. (2016) RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell 27:1346-57
Zieske, Katja; Chwastek, Grzegorz; Schwille, Petra (2016) Protein Patterns and Oscillations on Lipid Monolayers and in Microdroplets. Angew Chem Int Ed Engl 55:13455-13459
Battle, Christopher; Broedersz, Chase P; Fakhri, Nikta et al. (2016) Broken detailed balance at mesoscopic scales in active biological systems. Science 352:604-7
Einav, Tal; Mazutis, Linas; Phillips, Rob (2016) Statistical Mechanics of Allosteric Enzymes. J Phys Chem B 120:6021-37
Thievessen, Ingo; Fakhri, Nikta; Steinwachs, Julian et al. (2015) Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen. FASEB J 29:4555-67
Ludington, William B; Ishikawa, Hiroaki; Serebrenik, Yevgeniy V et al. (2015) A systematic comparison of mathematical models for inherent measurement of ciliary length: how a cell can measure length and volume. Biophys J 108:1361-1379

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