The principle objective of this application is to identify the impact on cognitive function of specific neuropathological changes found in Alzheimer's Disease. The study will be conducted in collaboration with a group of neurologists from the Maine Medical Center. Participating AD patients will serve as candidates for further research; efforts will be made to follow each patient to autopsy to expand an AD brain data bank. To determine whether cognitive integrative functions are impaired in AD, multiple aspects of grouping processes will be compared between AD patients and demographically-matched control subjects. Comparisons will also be made between young and elderly healthy control subjects to assess the effects of aging on these capacities. Analyses will be made of processes that mediate the segregation and association of discrete elements, the processing of identifiable configurations, and the processing of global relationships.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Academic Research Enhancement Awards (AREA) (R15)
Project #
1R15AG013758-01A2
Application #
2694267
Study Section
Human Development and Aging Subcommittee 3 (HUD)
Project Start
1998-09-01
Project End
1999-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Bowdoin College
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Brunswick
State
ME
Country
United States
Zip Code
04011
Kurylo, Daniel D (2006) Effects of aging on perceptual organization: efficacy of stimulus features. Exp Aging Res 32:137-52
Kurylo, Daniel D; Allan, Walter C; Collins, T Edward et al. (2003) Perceptual organization based upon spatial relationships in Alzheimer's disease. Behav Neurol 14:19-28