Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21DK073254-01
Application #
7017340
Study Section
Gastrointestinal Mucosal Pathobiology Study Section (GMPB)
Program Officer
Hamilton, Frank A
Project Start
2006-04-01
Project End
2007-12-31
Budget Start
2006-04-01
Budget End
2006-12-31
Support Year
1
Fiscal Year
2006
Total Cost
$212,500
Indirect Cost

  Institution

Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Zamakhchari, Maram; Wei, Guoxian; Dewhirst, Floyd et al. (2011) Identification of Rothia bacteria as gluten-degrading natural colonizers of the upper gastro-intestinal tract. PLoS One 6:e24455
Helmerhorst, Eva J; Zamakhchari, Maram; Schuppan, Detlef et al. (2010) Discovery of a novel and rich source of gluten-degrading microbial enzymes in the oral cavity. PLoS One 5:e13264
Freitag, T L; Rietdijk, S; Junker, Y et al. (2009) Gliadin-primed CD4+CD45RBlowCD25- T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice. Gut 58:1597-605
Schuppan, Detlef; Junker, Yvonne; Barisani, Donatella (2009) Celiac disease: from pathogenesis to novel therapies. Gastroenterology 137:1912-33
Schuppan, Detlef; Kelly, Ciaran P (2008) Is duodenal biopsy required in all patients with suspected celiac disease? Nat Clin Pract Gastroenterol Hepatol 5:70-1
Schuppan, Detlef; Junker, Yvonne (2007) Turning swords into plowshares: transglutaminase to detoxify gluten. Gastroenterology 133:1025-8
Schuppan, Detlef; Kelly, Ciaran P; Krauss, Norbert (2006) Monitoring non-responsive patients with celiac disease. Gastrointest Endosc Clin N Am 16:593-603