The long term goal of this work is to develop a surgical planning package to aid in the pre-operative and post-operative management of dialysis access sites. The package will consist of an ultrasound imaging system that provides 3D anatomical and flow velocity information, and a Fluid Structure Interaction model. The computational model will utilize the anatomical and flow velocity information for pre-treatment planning, prediction of post-treatment outcome, and correlation of post-treatment response with the computationally-derived hemodynamic parameters. In the long-term, the imaging and analysis package will allow a surgeon to virtually test dialysis access configurations prior to the surgical procedure. This surgical planning package is expected to increase the lifetime of access sites and reduce the number of dialysis access surgery cases that require secondary intervention, thereby improving patient outcomes and reducing costs. Since this package is ultrasound based, it is non-invasive and can safely and cost-effectively follow patients over time. We have already developed the ultrasound imaging capabilities to support this project;therefore this grant is focused on the development of the Fluid Structure Interaction simulation.

Public Health Relevance

The long term goal of this work is to develop a surgical planning package to aid in the pre-operative and post-operative management of dialysis access sites. Since this planning package will be entirely based on ultrasound imaging, it is non-invasive, safe and cost-effective. This surgical planning package is expected to increase the lifetime of access sites and reduce the number of dialysis access surgery cases that require secondary intervention, thereby improving patient outcomes and reducing costs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21DK081823-02
Application #
7686738
Study Section
Biomedical Computing and Health Informatics Study Section (BCHI)
Program Officer
Eggers, Paul Wayne
Project Start
2008-09-11
Project End
2011-08-31
Budget Start
2009-09-01
Budget End
2011-08-31
Support Year
2
Fiscal Year
2009
Total Cost
$234,192
Indirect Cost
Name
University of Washington
Department
Physics
Type
Schools of Earth Sciences/Natur
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
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