The long-term objective of this research is the development of an integrated high frequency ultrasound (HFUS) transducer system for quantitative imaging of skin and subcutaneous tissues for detection and characterization of abnormalities, e.g. skin tumors. If successful, the integrated system could provide a blueprint for image-guided surgery of skin tumors using high intensity focused ultrasound (HIFU), where quantitative imaging of the viscoelastic properties will provide robust means of guidance, monitoring and assessment of the surgery. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21EB006893-02
Application #
7364614
Study Section
Special Emphasis Panel (ZRG1-SBMI-S (10))
Program Officer
Lopez, Hector
Project Start
2007-03-01
Project End
2010-02-28
Budget Start
2008-03-01
Budget End
2010-02-28
Support Year
2
Fiscal Year
2008
Total Cost
$166,488
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
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Ebbini, Emad S; Bischof, John C (2009) Monitoring and guidance of minimally-invasive thermal therapy using diagnostic ultrasound. Conf Proc IEEE Eng Med Biol Soc 2009:4283, 4285-6
Wan, Yayun; Ebbini, Emad S (2009) A post-beamforming 2-D pseudoinverse filter for coarsely sampled ultrasound arrays. IEEE Trans Ultrason Ferroelectr Freq Control 56:1888-902
Wan, Yayun; Ebbini, Emad S (2009) A 2D post-beamforming filter for contrast restoration in medical ultrasound: in vivo results. Conf Proc IEEE Eng Med Biol Soc 2009:1945-8
Liu, Dalong; Ebbini, Emad S (2009) Real-time two-dimensional temperature imaging using ultrasound. Conf Proc IEEE Eng Med Biol Soc 2009:1971-4
Guzina, Bojan B; Tuleubekov, Kairat; Liu, Dalong et al. (2009) Viscoelastic characterization of thin tissues using acoustic radiation force and model-based inversion. Phys Med Biol 54:4089-112
Liu, Dalong; Ebbini, Emad S (2008) Viscoelastic property measurement in thin tissue constructs using ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control 55:368-83