The proposed project will utilize the comprehensive dataset from the Vision in Preschoolers (VIP) Study, a multi-center, cross-sectional, two-phased study sponsored by the National Eye Institute, to address unanswered questions that are of clinical and public health importance in vision screening.
The specific aims of this proposal do not include the major goals of the VIP Study, which were already accomplished and published. Instead, the proposed project involves the additional analysis of the VIP data to address the following important new aims, some of which were raised by experts during the National Eye Institute-sponsored Expert Panel Meeting in July 2005: (1) Evaluate the validity of noncycloplegic retinoscopy, Retinomax Autorefractor, SureSight Vision Screener, and Lea Symbols VA test for detecting VIP-defined hierarchical Group 1 conditions only (most severe), Group 1 &2 conditions (most and moderately severe), all VIP-targeted vision conditions, and for detecting each specific type of refractive error (myopia, hyperopia, astigmatism, and anisometropia) with various levels of severity, by using receiver operating characteristic (ROC) analysis. Make ROC results available to the public through an interactive, user- friendly website. (2) Examine the relation between anisometropia and unilateral amblyopia and between bilateral high refractive error and bilateral amblyopia, and the differences in their relation as a function of age of the child. (3) Determine the ethnic-specific prevalence of VIP-targeted vision conditions among Head Start preschool children. The VIP dataset is a unique resource to evaluate the operating characteristics of the best-performing vision screening tools that are now being used widely by organizations that conduct preschool vision screening, and to better understand vision conditions among preschoolers. The very large sample size (N=4,040), as well as the experience and high productivity of the VIP Study Group, support the feasibility and likelihood of high yield of the proposed project.
The proposed project will fully evaluate four well-performing vision screening tools and assess vision disorders in preschoolers. It will provide valuable information on the best use of these vision screening tools for the early detection and treatment of vision disorders, thus it has public health importance in vision screening.
| Kulp, Marjean Taylor; Ying, Gui-Shuang; Huang, Jiayan et al. (2014) Accuracy of noncycloplegic retinoscopy, retinomax autorefractor, and SureSight vision screener for detecting significant refractive errors. Invest Ophthalmol Vis Sci 55:1378-85 |
| Kulp, Marjean Taylor; Ying, Gui-Shuang; Huang, Jiayan et al. (2014) Associations between hyperopia and other vision and refractive error characteristics. Optom Vis Sci 91:383-9 |
| Pascual, Maisie; Huang, Jiayan; Maguire, Maureen G et al. (2014) Risk factors for amblyopia in the vision in preschoolers study. Ophthalmology 121:622-9.e1 |
| Ciner, Elise B; Ying, Gui-Shuang; Kulp, Marjean Taylor et al. (2014) Authors' response. Optom Vis Sci 91:e157-8 |
| Ciner, Elise B; Ying, Gui-Shuang; Kulp, Marjean Taylor et al. (2014) Stereoacuity of preschool children with and without vision disorders. Optom Vis Sci 91:351-8 |
| Ying, Gui-shuang; Maguire, Maureen G; Cyert, Lynn A et al. (2014) Prevalence of vision disorders by racial and ethnic group among children participating in head start. Ophthalmology 121:630-6 |
| Huang, Jiayan; Maguire, Maureen G; Ciner, Elise et al. (2014) Risk factors for astigmatism in the Vision in Preschoolers Study. Optom Vis Sci 91:514-21 |
| Ying, Gui-Shuang; Huang, Jiayan; Maguire, Maureen G et al. (2013) Associations of anisometropia with unilateral amblyopia, interocular acuity difference, and stereoacuity in preschoolers. Ophthalmology 120:495-503 |
| Huang, Jiayan; Maguire, Maureen G; Ciner, Elise et al. (2013) Intertester agreement in refractive error measurements. Optom Vis Sci 90:1128-37 |
| Vision in Preschoolers (VIP) Study Group; Ciner, Elise; Carter, Ashanti et al. (2011) Comparison of the Retinomax and Palm-AR Auto-Refractors: a pilot study. Optom Vis Sci 88:830-6 |
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