In 2009, 192,370 new cases of female breast cancer (BC) were diagnosed in the U.S. Of these cases, 5%- 10% were attributed to BRCA mutations. This translates to approximately 9,000 to18,000 high-risk women who may be impacted by hereditary BC. In a given year, the number of high-risk BC patients is similar to or greater than the total number of cases of other cancers in women (e.g., oral cancer, n=10,480;stomach cancer, n=8,310;cervical cancer n=11,720;myeloma n=8,900). While, the relative proportion of BC patients at increased risk for hereditary BC may be considered small, the absolute number is comparable to the total number of female cases in certain cancer sites. Recent studies suggest BC patients with a BRCA mutation have a 3.5 to 4.5 times greater risk of contralateral breast cancer (CBC) than patients without a BRCA mutation. Thus, thousands of women each year not only face a current BC diagnosis but are also at significantly increased CBC risk. There are criteria put forth by several leading health and professional organizations including the National Comprehensive Cancer Network that help providers readily identify women at increased risk for hereditary BC(e.g., diagnosis

Public Health Relevance

The proposed study, Genetic Education To Promote Counseling Attendance after Surgical Treatment (GET PAST) study will develop and evaluate a psychoeducational intervention (PEI) for high-risk, recently diagnosed, breast cancer patients about genetic counseling (GC).

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21HG006415-01
Application #
8206045
Study Section
Special Emphasis Panel (ZRG1-CRE-B (01))
Program Officer
Mcewen, Jean
Project Start
2011-09-13
Project End
2013-06-30
Budget Start
2011-09-13
Budget End
2012-06-30
Support Year
1
Fiscal Year
2011
Total Cost
$250,500
Indirect Cost
Name
H. Lee Moffitt Cancer Center & Research Institute
Department
Type
DUNS #
139301956
City
Tampa
State
FL
Country
United States
Zip Code
33612