We will utilize already-existing data that have been obtained by the NHLBI- sponsored Resuscitation Outcomes Consortium (ROC). Although the ROC generates vast quantities of resuscitation data, ROC investigators have been unable to maximize these due to the labor-intensive nature of the type of work we propose. Studying patients who experience out-of-hospital cardiac arrest, we will determine the incidence of re-arrest in patients who achieve a return of spontaneous circulation (ROSC) during the prehospital phase of their care. We believe that by developing a better understanding of the incidence and outcomes of re-arrest, the electrocardiographic (ECG) characteristics that indicate impending re-arrest, and clinical variables that affect re-arrest, more patients can be helped to survive.

Public Health Relevance

We are proposing to use already-existing data from the Resuscitation Outcomes Consortium (ROC) in order to determine the incidence of re-arrest in patients who suffer an out-of-hospital cardiac arrest, after getting a pulse back during their pre-hospital care. We will also determine their clinical outcomes (admission to the hospital and survival). We will determine whether information contained in the electrocardiogram (ECG) can be used to identify which patients are likely to re-arrest.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21HL104440-02
Application #
8278578
Study Section
Clinical and Integrative Cardiovascular Sciences Study Section (CICS)
Program Officer
Cook, Nakela L
Project Start
2011-06-10
Project End
2013-08-31
Budget Start
2012-06-01
Budget End
2013-08-31
Support Year
2
Fiscal Year
2012
Total Cost
$189,375
Indirect Cost
$64,375
Name
University of Pittsburgh
Department
Emergency Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Koller, Allison C; Salcido, David D; Callaway, Clifton W et al. (2014) Resuscitation characteristics and outcomes in suspected drug overdose-related out-of-hospital cardiac arrest. Resuscitation 85:1375-9
Koller, Allison C; Salcido, David D; Menegazzi, James J (2014) Physician and nonphysician health-care provider perspectives on resuscitation of suspected drug-related out-of-hospital cardiac arrest. Prehosp Emerg Care 18:483-8