The Southeastern Kidney Transplant (SEKTx) Coalition is an academic-community collaboration between partners in the kidney disease community who share the common goal of eliminating health disparities in access to kidney transplantation (KTx) among African American End Stage Renal Disease (ESRD) living in Georgia, North Carolina, and South Carolina. Volunteer members of this community-based coalition include ESRD and transplant patients, dialysis facility staff and providers, transplant centers, quality improvement organizations, and patient advocacy organizations. The burden of CKD and ESRD is highest in the Southeast, and yet the rate of KTx is the lowest in the nation. Further, our research suggests that racial disparities in access to KTx are concentrated in the Southeast, where African Americans (AA) are less likely to access each step in the KTx process. The long-term goal of the SEKTx Coalition is to use community- based participatory research approaches to develop, test, and disseminate sustainable, community interventions improve access to KTx for AA ESRD patients. In this planning grant, our specific aims are:
Specific Aim 1. To determine the patient-, dialysis facility-, and neighborhood-level barriers to KTx in ESRD Network 6.
Specific Aim 2 : To develop a multilevel intervention to reduce racial disparities in access to KTx.
Specific Aim 3 : To determine the feasibility and effectiveness of a pilot intervention to reduce disparities in'KTx access in GA. The long-term impact of this application will be to reduce racial disparities in the kidney disease community.

Public Health Relevance

The burden of CKD and ESRD is highest in the Southeast, and yet the rate of KTx is the lowest in the nation. The proposed study seeks to leverage an existing academic-community collaboration with the Southeastern Kidney Transplant Coalition to identify barriers to KTx and to plan, implement, and evaluate a multilevel intervention targeting ESRD patients and dialysis facility staff.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Resource-Related Research Projects (R24)
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Special Emphasis Panel (ZMD1-RN (07))
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Dankwa-Mullan, Irene
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Emory University
Schools of Medicine
United States
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Plantinga, Laura C; Patzer, Rachel E; Drenkard, Cristina et al. (2015) Association of time to kidney transplantation with graft failure among U.S. patients with end-stage renal disease due to lupus nephritis. Arthritis Care Res (Hoboken) 67:571-81
Patzer, Rachel E; Mohan, Sumit; Kutner, Nancy et al. (2015) Racial and ethnic disparities in pediatric renal allograft survival in the United States. Kidney Int 87:584-92
Mohan, Sumit; Mutell, Richard; Patzer, Rachel E et al. (2014) Kidney transplantation and the intensity of poverty in the contiguous United States. Transplantation 98:640-5
Patzer, R E; Pastan, S O (2014) Kidney transplant access in the Southeast: view from the bottom. Am J Transplant 14:1499-505
Plantinga, Laura C; Kim, Min; Goetz, Margarethe et al. (2014) Pre-end-stage renal disease care not associated with dialysis facility neighborhood poverty in the United States. Am J Nephrol 39:50-8
Plantinga, Laura; Pastan, Stephen; Kramer, Michael et al. (2014) Association of U.S. Dialysis facility neighborhood characteristics with facility-level kidney transplantation. Am J Nephrol 40:164-73
Patzer, Rachel E; Gander, Jennifer; Sauls, Leighann et al. (2014) The RaDIANT community study protocol: community-based participatory research for reducing disparities in access to kidney transplantation. BMC Nephrol 15:171
Patzer, R E; Plantinga, L; Krisher, J et al. (2014) Dialysis facility and network factors associated with low kidney transplantation rates among United States dialysis facilities. Am J Transplant 14:1562-72
Patzer, R E; Sayed, B A; Kutner, N et al. (2013) Racial and ethnic differences in pediatric access to preemptive kidney transplantation in the United States. Am J Transplant 13:1769-81