We are requesting a continuation of R25 CA089017, Multidisciplinary Training in Image-guided Therapy (IGT) at the Brigham and Women's Hospital. As we close in on the end of the second cycle, we are eager to continue on a successful track record in training MD and PhD fellows in the principles and practices of image-guided therapy for the treatment of cancer and cancer- related illnesses. To this end, we have prepared an application that has retained the most successful features of the training program that includes the most recent research occurring within the National Center for Image Guided Therapy (www.ncigt.org) (P41 EB015898, previously P41 RR019703) as well as in other relevant areas of the hospital community. The NCIGT provides a unique centralized infrastructure for clinical investigators, biomedical engineers, and basic scientists in promoting and advancing IGT methods and related clinical applications primarily aimed at the detection, diagnosis, and treatment of cancer. Fellows have the NCIGT efforts and new innovative technologies made available to them through seven training units: 1) Imaging;2) Computation;3) Tumor Ablation;4) Focused Ultrasound;5) Image-guided Neurosurgery;6) Image-guided Prostate Therapy;and 7) the Advanced Multimodality Image-Guided Operating (AMIGO) suite. The AMIGO, which is our new operating suite at the Brigham devoted to image-guided therapy, is a main area for Fellows to receive education and training and to initiate and complete cancer-focused research projects. At the outset of this two-year fellowship, trainees work with the PI, the Director of Education, and a senior faculty member/mentor to tailor an educational program that best meets the individual's needs and career goals. Fellows are exposed to both a specialized and a didactic curriculum, while concentrating on a specific area of cancer research. Additional mentors are assigned according to """"""""Individual Training Plans."""""""" While each training program is unique, all fellows are required to engage in a research project of considerable duration and produce a """"""""mock"""""""" or a real NIH grant application that is evaluated and reviewing internally. The PI, Advisory Committee, senior mentors, and other mentors, (depending on the research topic), take part in these reviews. The PI and Advisory Committee also provide oversight and strategic planning by 1) developing and refining a general recruitment plan and one targeted for underserved populations and women;2) assessing curriculum design and content;3) identifying trends in IGT research and training;and 4) making recommendations on the selection of fellows and placement in the program.
This educational grant (R25 CA089017), the Multidisciplinary Training in Image-guided Therapy (IGT) at the Brigham and Women's Hospital, also known as the Image-Guided Therapy Fellowship, provides a unique program to allow for the expansion and learning of image guided therapy of cancer for the broad healthcare community. Image-guided therapy of cancer requires the training of medical doctors and scientists, who can work with the complex advanced technology that can diagnose, localize and treat tumors in the same clinical setting. By providing multidisciplinary training to many different individuals, we can expand the pool of experts with new treatment modalities in IGT across other centers and various clinical settings.
|Ciris, Pelin Aksit; Cheng, Cheng-Chieh; Mei, Chang-Sheng et al. (2017) Dual-Pathway sequences for MR thermometry: When and where to use them. Magn Reson Med 77:1193-1200|
|Glazer, Daniel I; Tatli, Servet; Shyn, Paul B et al. (2017) Percutaneous Image-Guided Cryoablation of Hepatic Tumors: Single-Center Experience With Intermediate to Long-Term Outcomes. AJR Am J Roentgenol 209:1381-1389|
|Glazer, Daniel I; Mayo-Smith, William W; Sainani, Nisha I et al. (2017) Interreader Agreement of Prostate Imaging Reporting and Data System Version 2 Using an In-Bore MRI-Guided Prostate Biopsy Cohort: A Single Institution's Initial Experience. AJR Am J Roentgenol 209:W145-W151|
|Glazer, Daniel I; Hassanzadeh, Elmira; Fedorov, Andriy et al. (2017) Diffusion-weighted endorectal MR imaging at 3T for prostate cancer: correlation with tumor cell density and percentage Gleason pattern on whole mount pathology. Abdom Radiol (NY) 42:918-925|
|Mallory, Melissa A; Sagara, Yasuaki; Aydogan, Fatih et al. (2017) Feasibility of Intraoperative Breast MRI and the Role of Prone Versus Supine Positioning in Surgical Planning for Breast-Conserving Surgery. Breast J 23:713-717|
|Essayed, Walid I; Zhang, Fan; Unadkat, Prashin et al. (2017) White matter tractography for neurosurgical planning: A topography-based review of the current state of the art. Neuroimage Clin 15:659-672|
|Fischer, K; Ohori, S; Meral, F C et al. (2017) Testing the Efficacy of Contrast-Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation. Am J Transplant 17:1791-1801|
|Hassanzadeh, Elmira; Glazer, Daniel I; Dunne, Ruth M et al. (2017) Prostate imaging reporting and data system version 2 (PI-RADS v2): a pictorial review. Abdom Radiol (NY) 42:278-289|
|O'Donnell, Lauren J; Suter, Yannick; Rigolo, Laura et al. (2017) Automated white matter fiber tract identification in patients with brain tumors. Neuroimage Clin 13:138-153|
|Todd, Nick; Josephs, Oliver; Zeidman, Peter et al. (2017) Functional Sensitivity of 2D Simultaneous Multi-Slice Echo-Planar Imaging: Effects of Acceleration on g-factor and Physiological Noise. Front Neurosci 11:158|
Showing the most recent 10 out of 98 publications