The UCLA Scholars in Oncologic Molecular Imaging (SOMI) is an integrated, cross-disciplinary postdoctoral training program bringing together faculty mentors from 7 departments and 6 divisions in the David Geffen School of Medicine, the College of Letters and Sciences, and the Henry Samueli School of Engineering and Applied Science. Molecular imaging, the non-invasive monitoring of specific molecules and biochemical process in living organisms, continues to expand its applications in the detection and management of cancer. SOMI faculty mentors provide a diverse training environment spanning mathematics, physics, engineering, chemistry, biochemistry, cancer biology, immunology, and medical sciences. The centerpiece of the SOMI program is the opportunity for trainees (Ph.D. or M.D.) to conduct innovative molecular imaging research co-mentored by faculty in complementary disciplines. SOMI trainees also engage in specialized coursework, seminars, a clinical tutorial program, and participate in a course on ethics and responsible research. The three-year program culminates in preparation of a mock grant, as trainees transition to independent careers in cancer molecular imaging. During the initial funding period, 19 trainees entered the SOMI program, and nine SOMI fellows have subsequently been appointed to faculty positions. In the renewal period, we propose to continue and strengthen the SOMI program through addition of a new Program Area (Systems Biology), strategic additions to our faculty mentors, and continuous improvement of the other training and career development components of the program. The goal of the SOMI program is to continue to provide talented young investigators with the scientific and professional training needed to become leaders in the field of molecular imaging of cancer.
TO PUBLIC HEALTH The UCLA Scholars in Oncologic Molecular Imaging (SOMI) program is an integrated, cross-disciplinary postdoctoral training program that prepares young investigators for research careers in the field of molecular imaging of cancer. Molecular imaging is a science that allows visualization of specific molecules and biochemical process in intact living organisms, and provides powerful tools for the study of disease. SOMI trainees develop innovative molecular imaging approaches for the detection, diagnosis and staging of cancer, as well as treatment selection and evaluation of responses.
|Graham, Nicholas A; Graeber, Thomas G (2014) Complexity of metastasis-associated SDF-1 ligand signaling in breast cancer stem cells. Proc Natl Acad Sci U S A 111:7503-4|
|Qi, Hangfei; Olson, C Anders; Wu, Nicholas C et al. (2014) A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity. PLoS Pathog 10:e1004064|
|Olson, C Anders; Wu, Nicholas C; Sun, Ren (2014) A comprehensive biophysical description of pairwise epistasis throughout an entire protein domain. Curr Biol 24:2643-51|
|Bunimovich, Yuri L; Nair-Gill, Evan; Riedinger, Mireille et al. (2014) Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance. PLoS One 9:e104125|
|Clark, Peter M; Flores, Graciela; Evdokimov, Nikolai M et al. (2014) Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. Proc Natl Acad Sci U S A 111:E2866-74|
|Thai, Minh; Graham, Nicholas A; Braas, Daniel et al. (2014) Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication. Cell Metab 19:694-701|
|Tavaré, Richard; Wu, Wei H; Zettlitz, Kirstin A et al. (2014) Enhanced immunoPET of ALCAM-positive colorectal carcinoma using site-specific ??Cu-DOTA conjugation. Protein Eng Des Sel 27:317-24|
|Tavaré, Richard; McCracken, Melissa N; Zettlitz, Kirstin A et al. (2014) Engineered antibody fragments for immuno-PET imaging of endogenous CD8+ T cells in vivo. Proc Natl Acad Sci U S A 111:1108-13|
|Gil, Jose S; Machado, Hidevaldo B; Campbell, Dean O et al. (2013) Application of a rapid, simple, and accurate adenovirus-based method to compare PET reporter gene/PET reporter probe systems. Mol Imaging Biol 15:273-81|
|Herrmann, Ken; Dahlbom, Magnus; Nathanson, David et al. (2013) Evaluation of the Genisys4, a bench-top preclinical PET scanner. J Nucl Med 54:1162-7|
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