The purpose of this Cancer Education and Career Development Program (CECDP) is preparing junior and more experienced basic scientists for the interdisciplinary research environment. The CECDP is primarily designed for experimental cancer researchers to obtain training in population science including cancer epidemiology, survival analysis, population genetics, pharmacogenetics, and statistical modeling of cancer. An important feature of the proposed program is that it focuses on integrating knowledge from population and experimental studies of cancer and establishes links between these different areas in both educational and scientific parts of the program. Such interdisciplinary focus is lacking in existing cancer training programs.
It aims to improve credibility of studies performed by experimental cancer researchers. The program will include: (l) six semesters of weekly seminars (conducted by both faculty and trainees) emphasizing connections between cancer biology and epidemiology;human and animal studies of cancer;cancer and aging;population genetics and epigenetics;cancer biomarkers and prevention;and statistical approaches to population and experimental studies of cancer;(2) research training and project in population science;(3) preparing scientific publications and mock grant application with the interdisciplinary focus, for further career development. The program will be based at the Duke Comprehensive Cancer Center's Research Program in Cancer Prevention, Detection, and Control, and will engage faculty, mentors, and Advisory Committee members from various Duke Departments, representing all the areas involved into this program. We plan to recruit four fellows who have completed doctorates in basic/experimental cancer biology/genetics. Recruitment will be undertaken on a national level, followed by personal interviews to identify postdoctoral candidates with strong motivation in interdisciplinary cancer research. Our multidisciplinary team of highly qualified faculty/mentors is capable to carry out both educational and research parts of this program. With support of comprehensive scientific resources of Duke University, this will provide a solid environment for the interdisciplinary training and career development proposed in the CECDP.

Public Health Relevance

The purpose of this Cancer Education and Career Development (CECD) program is to prepare both junior and more experienced basic scientists for the interdisciplinary research environment. The CECD program is primarily designed for experimental cancer researchers to obtain training in population science, including cancer epidemiology, statistical analysis, genetic epidemiology pharmacogenetics and health behavior.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Education Projects (R25)
Project #
5R25CA126938-05
Application #
8535616
Study Section
Subcommittee G - Education (NCI)
Program Officer
Perkins, Susan N
Project Start
2009-09-01
Project End
2014-08-31
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
5
Fiscal Year
2013
Total Cost
$272,691
Indirect Cost
$23,609
Name
Duke University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Scarbrough, Peter M; Akushevich, Igor; Wrensch, Margaret et al. (2014) Exploring the association between melanoma and glioma risks. Ann Epidemiol 24:469-74
Allott, Emma H; Howard, Lauren E; Song, Hai-Jun et al. (2014) Racial differences in adipose tissue distribution and risk of aggressive prostate cancer among men undergoing radiotherapy. Cancer Epidemiol Biomarkers Prev 23:2404-12
Allott, E H; Abern, M R; Gerber, L et al. (2013) Metformin does not affect risk of biochemical recurrence following radical prostatectomy: results from the SEARCH database. Prostate Cancer Prostatic Dis 16:391-7
Allott, Emma H; Masko, Elizabeth M; Freedland, Stephen J (2013) Obesity and prostate cancer: weighing the evidence. Eur Urol 63:800-9
Soubry, Adelheid; Schildkraut, Joellen M; Murtha, Amy et al. (2013) Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort. BMC Med 11:29
Vidal, A C; Murphy, S K; Murtha, A P et al. (2013) Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. Int J Obes (Lond) 37:907-13
Masko, Elizabeth M; Allott, Emma H; Freedland, Stephen J (2013) The relationship between nutrition and prostate cancer: is more always better? Eur Urol 63:810-20
Soubry, Adelheid; Il'yasova, Dora; Sedjo, Rebecca et al. (2012) Increase in circulating levels of IGF-1 and IGF-1/IGFBP-3 molar ratio over a decade is associated with colorectal adenomatous polyps. Int J Cancer 131:512-7